Extraction of milk oligosaccharides from lactose mother liquor : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Bioprocess Engineering at Massey University, Manawatū, New Zealand. EMBARGOED until 4 December 2017
Oligosaccharides are a diverse range of sugars, similar to lactose in structure, that are found in relatively high concentrations in human milk. Their effects in breast-fed infants include improved brain development, resistance to infection, and colonisation of the lower gut with beneficial bacteria. Milk from other mammals, including infant formula based on cow's milk, has a much lower concentration of oligosaccharides. Mr Peacey researched separation techniques to extract oligosaccharides from dairy by-products for addition to infant formula. His research focussed on simulated moving bed chromatography, a continuous separation of two fractions of a liquid stream based on molecular size difference, using columns filled with gel media. A four-column laboratory apparatus was built and used to confirm modelling results, showing that the process achieves the separation with relatively high purity and throughput. His research contributes to understanding of simulated moving bed technology and its application in dairy processing.