Mental health is a prevalent, but often ignored area of health. Mental illness can significantly impact the mentally unwell, their families, and the wider community, yet access to proper care can be hindered by availability, ignorance, discrimination, and stigma, and result in human rights violations. This is especially true in developing countries where services may be inadequate or non-existent. Mental health policies can alleviate this situation by improving and prioritising mental health services at a national level. Based on Samoa and Niue’s similarities in terms of their mental health context and the positive analysis and evaluation of the 2006 Samoan policy, this paper concludes that the work done in Samoa is a viable choice for Niue to leverage in their future policy work. Niue would benefit from developing their mental health policy based on the precepts of South-to-South Cooperation by collaborating and sharing knowledge with their neighbour Samoa.