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                  <mods:namePart>Gozho, Nhamo George</mods:namePart>
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                  <mods:dateAccessioned encoding="iso8601">2014-05-12T22:55:57Z</mods:dateAccessioned>
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                  <mods:dateIssued encoding="iso8601">1995</mods:dateIssued>
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               <mods:identifier type="uri">http://hdl.handle.net/10179/5354</mods:identifier>
               <mods:identifier type="wikidata">Q112851654</mods:identifier>
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               <mods:abstract>lonophore supplements are widely used in the ration of fattening beef cattle,&#xd;
especially in the United States. Studies have indicated benefits in terms of a&#xd;
faster growth rate and live weight gain and a reduction in feed intake in beef&#xd;
cattle fed either monensin or lasalocid. In recent years interest has been&#xd;
growing on the possible use of ionophores in dairy cattle. This is because&#xd;
changes in rumen metabolism associated with ionophores could increase milk&#xd;
production in lactating ruminants and/or reduce health and reproductive&#xd;
problems.&#xd;
Two experiments were conducted with dairy cows at grazing to evaluate the&#xd;
effects of Bovatec 20 (lasalocid) on milk production and performance in early&#xd;
and mid-lactation. In Experiment 1 thirty multiparous Friesian cows aged&#xd;
between three and nine years were assigned to two similar treatment groups&#xd;
of 15 cows balanced for age, previous lactation production, body weight and&#xd;
body condition prior to calving. Treatments consisted of no lasalocid (control)&#xd;
and 400 mg lasalocid per cow per day (drenched twice daily) and the&#xd;
experiment commenced 7 days postpartum. Milk yield and composition were&#xd;
measured at weekly intervals and the treatment continued for ten weeks.&#xd;
Gross energy content of milk was estimated from milk composition. Blood was&#xd;
sampled by tail venipuncture at weekly intervals during morning milking and&#xd;
serum harvested. Serum was analyzed for concentrations of non-esterified&#xd;
fatty acids, B-hydroxybutyrate, glucose, magnesium and calcium.&#xd;
Reproductive parameters (calving to first oestrus, calving to conception&#xd;
intervals and the number of services per conception) were calculated from&#xd;
farm records collected during the experiment.&#xd;
No differences in milk, milk fat, protein, or lactose yields were observed.&#xd;
Significant (P&lt;0.01) lasalocid by period interaction was observed for milk fat&#xd;
yield. Gross energy content in milk did not differ between groups but period&#xd;
effects were significant (P&lt;O.lO) during weeks 3, 6, 7 and 9. Period by&#xd;
lasalocid interaction for gross energy content of milk was also significant&#xd;
(P&lt;0.1 0). Lasalocid treatment did not affect live weight changes of cows in&#xd;
early lactation. Lasalocid treated cows lost significantly (P&lt;0.05) more&#xd;
condition than control cows. Plasma concentrations of B-hydroxybutyrate,&#xd;
non-esterified fatty acids, glucose, magnesium and calcium were unaffected&#xd;
by lasalocid. Period by lasalocid effects for non esterified fatty acids and for&#xd;
magnesium were significant (P&lt;0.05 and P&lt;0.10, respectively). Reproductive&#xd;
parameters were unaffected by lasalocid supplementation.&#xd;
In Experiment 2 forty-five multiparous Friesian cows in mid-lactation were&#xd;
divided into three groups using the criteria as in Experiment 1. The groups&#xd;
were randomly allocated to three treatments. Treatments consisted of a&#xd;
control group, a group treated with Bovatec 20 (lasalocid) as in Experiment 1,&#xd;
and a third group treated with Bloatenz (a bloat preventive formulation).&#xd;
Treatments lasted 10 weeks. Milk yield and composition, live weight and body&#xd;
condition scores were measured as in Experiment 1. Cows were also scored&#xd;
for intensity of bloat for two periods each of 7 days.&#xd;
Treatment with either Bovatec 20 or Bloatenz did not affect milk, fat, protein&#xd;
or lactose yields of cows in mid-lactation. Period effects for fat yield were&#xd;
significant (P&lt;0.05). Gross energy content in milk was unaffected by&#xd;
treatment. Live weight changes were unaffected by treatments but cows&#xd;
treated with Bovatec 20 and Bloatenz lost less condition compared to control&#xd;
cows. The pastures used failed to induce bloat and hence there were no data&#xd;
for this aspect of the study.&#xd;
It was concluded that feeding lasalocid resulted in only small numerical&#xd;
increases in milk production in early lactation with no milk production&#xd;
responses in mid-lactation. Lasalocid had minor negative influence on body&#xd;
condition in early lactation and a significant positive influence in mid-lactation.</mods:abstract>
               <mods:language>
                  <mods:languageTerm authority="rfc3066">en</mods:languageTerm>
               </mods:language>
               <mods:accessCondition type="useAndReproduction">The Author</mods:accessCondition>
               <mods:subject>
                  <mods:topic>Ionophore supplements</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Dairy cattle feed</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Milk production</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Bovatec</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Lasalocid</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Bloatenz</mods:topic>
               </mods:subject>
               <mods:titleInfo>
                  <mods:title>The effects of lasalocid on milk production in pastured spring-calving dairy cows : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Agricultural Science at Massey University</mods:title>
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