O'Donnell J5/07/20195/07/2019J Respir Dis Med, 20192633-1063https://hdl.handle.net/10179/17194Copyright: ©2019 Donnell JO. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are creditedMore than fifteen years ago clinicians’ saw the introduction of a new form of noninvasive respiratory support which is now commonly known as Nasal High Flow (NHF) therapy. Today this therapy is used throughout hospitals and, in the home settings. This narrative review of the evidence will characterize: NHF mechanisms of action, therapeutic efficacy, contemporary delivery, and strategies for clinical applications.Journal article453790Massey_Dark