Now showing items 1-10 of 32
Antigen-specific cytotoxic T lymphocytes target airway CD103+ and CD11b+ dendritic cells to suppress allergic inflammation
(Nature Publishing Group, 2016-01)
Allergic airway inflammation is driven by the recognition of inhaled allergen by T helper type 2 (Th2) cells in the airway and lung. Allergen-specific cytotoxic T lymphocytes (CTLs) can strongly reduce airway inflammation, ...
Empirical evaluation of sustainability of divergent farms in the dryland farming systems of India
The present study argues that there are heterogeneous farm systems within the drylands and each farm system is unique in terms of its livelihood asset and agricultural practice, and therefore in sustainability. Our method ...
Preferential sites for intramolecular glucosepane cross-link formation in type I collagen: A thermodynamic study
The extracellular matrix (ECM) undergoes progressive age-related stiffening and loss of proteolytic digestibility due to an increase in concentration of advanced glycation end products (AGEs). The most abundant AGE, ...
Transient Hypermutagenesis Accelerates the Evolution of Legume Endosymbionts following Horizontal Gene Transfer
(PUBLIC LIBRARY SCIENCE, 2014-09-01)
Obligate mutualism within a host drives the extreme specialization of a fig wasp genome.
BACKGROUND: Fig pollinating wasps form obligate symbioses with their fig hosts. This mutualism arose approximately 75 million years ago. Unlike many other intimate symbioses, which involve vertical transmission of symbionts ...
Evolutionary History of Rabies in Ghana
Intra-molecular lysine-arginine derived advanced glycation end-product cross-linking in Type I collagen: A molecular dynamics simulation study.
Covalently cross-linked advanced glycation end products (AGE) are among the major post-translational modifications to proteins as a result of non-enzymatic glycation. The formation of AGEs has been shown to have adverse ...