Now showing items 1-10 of 30
A model for phenotype change in a stochastic framework
(American Institute of Mathematical Sciences, 2010)
some species, an inducible secondary phenotype will develop some time after the environmental change that evokes it. Nishimura (2006)  showed how an individual organism should optimize the time it takes to respond to ...
Impact of Genetic Background on Allele Selection in a Highly Mutable Candida albicans Gene, PNG2
In many microbes rapid mutation of highly mutable contingency genes continually replenishes a pool of variant alleles from which the most suitable are selected, assisting in rapid adaptation and evasion of the immune ...
Testing the Effect of Metabolic Rate on DNA Variability at the Intra-Specific Level
(PLoS One, 2010-03-15)
We tested the metabolic rate hypothesis (whereby rates of mtDNA evolution are postulated to be mediated primarily by mutagenic by-products of respiration) by examining whether mass-specific metabolic rate was correlated ...
Quantifying Risk Factors for Human Brucellosis in Rural Northern Tanzania
(PLoS One, 2010-04-01)
Background: Brucellosis is a zoonosis of veterinary, public health and economic significance in most developing countries. Human brucellosis is a severely debilitating disease that requires prolonged treatment with a ...
Cytotoxic Aggregation and Amyloid Formation by the Myostatin Precursor Protein
Myostatin, a negative regulator of muscle growth, has been implicated in sporadic inclusion body myositis (sIBM). sIBM is the most common age-related muscle-wastage disease with a pathogenesis similar to that of amyloid ...
Survival disparities in Indigenous and non-Indigenous New Zealanders with colon cancer: the role of patient comorbidity, treatment and health service factors
(BMJ Publishing Group, 2010-02)
Background Ethnic disparities in cancer survival have been documented in many populations and cancer types. The causes of these inequalities are not well understood but may include disease and patient characteristics, ...
Within and between Whorls: Comparative Transcriptional Profiling of Aquilegia and Arabidopsis
Background: The genus Aquilegia is an emerging model system in plant evolutionary biology predominantly because of its wide variation in floral traits and associated floral ecology. The anatomy of the Aquilegia flower is ...
Exploring The Responsibilities Of Single-Inhabitant Smart Homes With Use Cases
(IOS Press, 2010-06)
This paper makes a number of contributions to the field of requirements analysis for Smart Homes. It introduces Use Cases as a tool for exploring the responsibilities of Smart Homes and it proposes a modification of the ...
Experiences of nursing in older care facilities in New Zealand
(CSIRO PUBLISHING, 2010-01-01)