Now showing items 1-10 of 32
Preferential sites for intramolecular glucosepane cross-link formation in type I collagen: A thermodynamic study
The extracellular matrix (ECM) undergoes progressive age-related stiffening and loss of proteolytic digestibility due to an increase in concentration of advanced glycation end products (AGEs). The most abundant AGE, ...
Transient Hypermutagenesis Accelerates the Evolution of Legume Endosymbionts following Horizontal Gene Transfer
(PUBLIC LIBRARY SCIENCE, 2014-09-01)
Obligate mutualism within a host drives the extreme specialization of a fig wasp genome.
BACKGROUND: Fig pollinating wasps form obligate symbioses with their fig hosts. This mutualism arose approximately 75 million years ago. Unlike many other intimate symbioses, which involve vertical transmission of symbionts ...
Intra-molecular lysine-arginine derived advanced glycation end-product cross-linking in Type I collagen: A molecular dynamics simulation study.
Covalently cross-linked advanced glycation end products (AGE) are among the major post-translational modifications to proteins as a result of non-enzymatic glycation. The formation of AGEs has been shown to have adverse ...
Let the Powers Combine
NAR Breakthrough Article Chromosome conformation maps in fission yeast reveal cell cycle dependent sub nuclear structure
(OXFORD UNIV PRESS, 2014-11-10)
Branched pectic galactan in phloem-sieve-element cell walls: Implications for cell mechanics
(American Society of Plant Biologists, 2018-02-06)
A major question in plant biology concerns the specification and functional differentiation of cell types. This is in the context of constraints imposed by networks of cell walls that both adhere cells and contribute to ...
An empirical analysis of the cost of rearing dairy heifers from birth to first calving and the time taken to repay these costs.
Rearing quality dairy heifers is essential to maintain herds by replacing culled cows. Information on the key factors influencing the cost of rearing under different management systems is, however, limited and many farmers ...
De novo transcriptome assembly, functional annotation and differential gene expression analysis of juvenile and adult E. fetida, a model oligochaete used in ecotoxicological studies.
BACKGROUND: Earthworms are sensitive to toxic chemicals present in the soil and so are useful indicator organisms for soil health. Eisenia fetida are commonly used in ecotoxicological studies; therefore the assembly of a ...
Single-molecule folding mechanisms of the apo- and Mg(2+)-bound states of human neuronal calcium sensor-1.
Neuronal calcium sensor-1 (NCS-1) is the primordial member of a family of proteins responsible primarily for sensing changes in neuronal Ca(2+) concentration. NCS-1 is a multispecific protein interacting with a number of ...