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dc.contributor.authorLucas-Roxburgh, Ren_US
dc.contributor.authorBenschop, Jen_US
dc.contributor.authorDunowska, Men_US
dc.contributor.authorPerrott, Men_US
dc.coverage.spatialNew Zealanden_US
dc.date.available2015-09-25en_US
dc.date.issued2015-09-25en_US
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/26411846en_US
dc.identifier.citationN Z Med J, 2015, 128 (1422), pp. 45 - 52en_US
dc.description.abstractAIM: Human papillomavirus (HPV) in the oral cavity has been retrospectively associated with an increased risk of developing HPV-positive head and neck squamous cell carcinoma (HNSCC). The aim of this study was to determine the prevalence of oral HPV infection in a local population of New Zealand women aged 18 to 25 years, including determination of HPV genotypes, and to assess potential risk factors for oral HPV infection using participant questionnaire responses. METHODS: Oral brushings and questionnaire responses were collected from 234 women recruited from sexual health and student health centres. Questions covered age, ethnicity, sexual partners, alcohol consumption and smoking. PGMY primers were used for HPV detection by PCR, and results confirmed by sequencing and the cobas® 4800 HPV system. RESULTS: The prevalence of HPV infection was 3.2% of 216 women (95% CI: 1.6%-6.5%). Samples from two women (0.9%, 95% CI: 0.3%-3.3%) contained oncogenic HPV, and another five (2.3%, 95% CI: 1.0%-5.3%) were positive for HPV 13. No significant associations were found between putative risk factors and the presence of oral HPV infection. CONCLUSION: The prevalence of HPV in the oral cavity of New Zealand woman was comparable to results of other studies, but showed an unusual distribution of HPV types. The comparatively high detection rate of HPV 13 suggests that further work into clinical significance of oral HPV 13 infection is warranted.en_US
dc.format.extent45 - 52en_US
dc.languageengen_US
dc.subjectAdolescenten_US
dc.subjectAdulten_US
dc.subjectCross-Sectional Studiesen_US
dc.subjectFemaleen_US
dc.subjectHead and Neck Neoplasmsen_US
dc.subjectHumansen_US
dc.subjectMouth Diseasesen_US
dc.subjectNew Zealanden_US
dc.subjectPapillomaviridaeen_US
dc.subjectPapillomavirus Infectionsen_US
dc.subjectPolymerase Chain Reactionen_US
dc.subjectPrevalenceen_US
dc.subjectRisk Factorsen_US
dc.subjectYoung Adulten_US
dc.titlePrevalence of human papillomaviruses in the mouths of New Zealand women.en_US
dc.typeJournal Article
dc.citation.volume128en_US
dc.identifier.elements-id259137
dc.relation.isPartOfN Z Med Jen_US
dc.citation.issue1422en_US
dc.identifier.eissn1175-8716en_US
dc.description.publication-statusPublished onlineen_US
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/Institute of Vet, Animal & Biomed Science
dc.identifier.harvestedMassey_Dark
pubs.notesNot knownen_US
dc.subject.anzsrc11 Medical And Health Sciencesen_US


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