Browsing by Author "Beggan CP"

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    Efficacy of needle and endoscopic lavage on the recuperation of microspheres from the adult equine metacarpo−/metatarsophalangeal joint and digital flexor tendon sheath
    (Wiley Periodicals LLC on behalf of American College of Veterinary Surgeons, 2025-06-25) Beggan CP; Panizzi L; Oliver LJ
    Objectives: To measure microsphere recovery following needle-through-and-through lavage (NTAT) of the metacarpo−/metatarsophalangeal joint (fetlock) and digital flexor tendon sheath (DFTS) compared to endoscopic lavage (EL). Study design: Ex vivo experimental study. Animals: Adult equine cadavers immediately following euthanasia (n = 10). Methods: Colored 15 μm microspheres (2 million) were injected into fetlock joints and DFTS. Synovial structures were assigned to NTAT or EL groups. Each lavage was performed using 5 L of 0.9% NaCl, sequentially collecting egress fluid for microsphere quantification. Recovery was compared using a full-factorial general linear model. Results: There was a significant effect of the liter of egress fluid and microsphere recovery in both fetlocks (p <.01) and DFTS (p <.01), with most microspheres recovered in the first 2 L (79%–83%) for both techniques. More microspheres were recovered in the first liter using NTAT than EL (p <.01) in both fetlocks (659 883 ± 20 820 vs. 567 601 ± 24 452) and DFTS (644 341 ± 17 460 vs. 550 637 ± 38 022). No difference in total recovered microspheres was observed between NTAT lavage of fetlock (981 600 ± 46 839) and DFTS (957 419 ± 45 729) across 5 L (p =.88). Conclusion: Needle-through-and-through lavage was more effective than EL at recovering microspheres in the first liter from cadaveric equine fetlock joints and DFTS. Both techniques demonstrated comparable efficacy between fetlock and DFTS in microsphere recovery following increased lavage volumes. Clinical significance: Needle-through-and-through lavage (NTAT) is a viable alternative for suspected synovial contamination when EL is delayed or not feasible. This study does not evaluate NTAT's efficacy for treating established sepsis or removing pannus/foreign bodies.
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    Mammary tubulopapillary carcinoma in a mare, requiring bilateral mastectomy.
    (Informa UK Limited, trading as Taylor & Francis Group, 2023-08-30) Beggan CP; Quinn GC; D'Amours GH
    Mammary neoplasia is uncommon in the mare and often mistaken for mastitis (Reppas et al. Citation1996). Incidence rates of mammary tumours in horses of 0.1–1.9% are reported, with carcinomas the most common (Brito et al. Citation2008). Due to the low incidence, and similarity of initial signs to those of mastitis, diagnosis is often delayed until after antibiotic and anti-inflammatory treatment has failed (Boyce and Goodwin Citation2017). Mares are often, therefore, presented in an advanced stage of disease with a poor prognosis (Ferreira Júnior et al. Citation2019). Due to the infrequency of mammary neoplasia in horses it has been difficult to develop an evidence based approach to treatment. Studies in domestic animals report a low success rate with conservative management of these neoplasms. Combined with their highly aggressive and metastatic nature, surgical excision has been perceived as the treatment of choice in the initial management of these neoplasms (Seahorn et al. Citation1992).