Browsing by Author "Karkaba, Ali"
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- ItemOccurrence and distribution of extended spectrum β-lactamase and AmpC-β-lactamase-producing Enterobacteriaceae and methicillin resistant Staphylococcus aureus in companion animals in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Microbiology, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand(Massey University, 2017) Karkaba, AliThe increasing incidence of infections with extended spectrum-lactamase (ESBL)- and AmpC-producing Enterobacteriaceae, and methicillin-resistant Staphylococcus aureus (MRSA) in humans in the last decade is a matter of concern. There is a paucity of data on the incidence of infections with these bacteria in animals, partly because veterinary diagnostic laboratories do not routinely test for these organisms in clinical specimens. The carriage rate of these bacteria by companion animals is also unknown. This PhD project aimed to investigate the occurrence of ESBL/AmpCproducing Enterobacteriaceae and MRSA in clinical specimens from animals in New Zealand, and examine the carriage of multidrug-resistant (MDR), ESBL/AmpC-E. coli, and MRSA in cats and dogs in Auckland. The results of this project indicate that ESBL/AmpC-producing E. coli and MRSA cause clinical infections in companion animals in New Zealand. The circulation of these bacteria is likely to be posing therapeutic challenges to unaware veterinarians. The bacteria causing infections or carried by companion animals are genetically similar to those found in humans in New Zealand, raising public health concerns about the role of carrier animals as potential sources of zoonotic infections.