Browsing by Author "Pozuelo JR"

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    Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
    (Elsevier B V, 2025-09-01) Roest AM; de Vries YA; Pozuelo JR; Petukhova MV; Lee S; Sampson NA; Albor Y; Alhadi AN; Alonso J; Al-Saud N; Altwaijri Y; Andersson C; Atwoli L; Auerbach RP; Muaka CA; Báez-Mansur PM; Ballester L; Bantjes J; Baumeister H; Bendtsen M; Benjet C; Berman AH; Bruffaerts R; Carrasco P; Chan SCN; Cohut I; Couder MAC; Crockett MA; Cuijpers P; David OA; Dong D; Ebert DD; Gaete J; Forero CG; Gili M; Gutiérrez-García R; Haro JM; Hasking P; Hunt X; Husky MM; Jaguga F; Langer ÁI; Léniz I; Liu Y; Mac-Ginty S; Martínez V; McLafferty M; Miranda A; Monroy-Velasco IR; Murray EK; Musyoka CM; Nedelcea C; Núñez D; O'Neill SM; Piqueras JA; Popescu CA; Prescivalli AP; Rapsey C; Robinson K; Rodriguez-Jimenez T; Saal W; Siu O-L; Stein DJ; Struijs SY; Tomoiaga CT; Valdés-García KP; Vargas-Contreras E; Vigo DV; Wang AY; Wong SYS; Kessler RC; World Mental Health International College Student collaborators
    Background: Mental disorders are highly prevalent among students worldwide. This study aims to examine comorbidity and temporal associations between mental disorders among students. Methods: The study included 72,288 students from 18 countries as part of the World Mental Health International College Student (WMH-ICS) Initiative, with cross-sectional data collected between 2017 and 2023. Screening for common DSM-5 disorders was conducted using validated screening measures. Latent variables were examined using exploratory principal axis factor analysis on a correlation matrix among the lifetime mental disorders. Based on age-of-onset information, multivariable poisson regression models were used to examine associations of prior disorders with the first onset of other disorders. Results: 27.0 % of students screened positive for only one lifetime disorder, 17.1 % for two, 10.9 % for three, and 10.6 % for 4+ disorders. In the factor analysis, three latent variables were found, comprising: internalizing disorders (generalized anxiety disorder, major depressive episode, post-traumatic stress disorder, and panic disorder), substance use disorders (drug use disorder and alcohol use disorder), and externalizing disorders (attention deficit/hyperactivity disorder and mania/hypomania). Prior internalizing and externalizing disorders were associated with the subsequent first onset of all other disorders with risk ratios ranging from 1.5–7.5. Substance use disorders were less consistently associated with the subsequent first onset of other disorders, but alcohol use disorder was associated with the first onset of drug use disorder and vice versa. Conclusions: Mental disorder comorbidity is common among students, and students with disorders across the internalizing and externalizing spectrum have an increased risk of future mental disorder comorbidities.