Browsing by Author "Whittington, Craig J"
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- ItemEffects of 50 Hz intermittent magnetic field exposure on human performance and cardiovascular response : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University(Massey University, 1995) Whittington, Craig JOne hundred subjects (aged 18-48 years) were exposed and sham exposed to a 100 μT intermittent magnetic field, modulated sinusoidally at 50 Hz. To examine the effect of field exposure on performance, a two alternative forced-choice duration discrimination task with 3 levels of difficulty was used. Cardiovascular response was also assessed using measures of blood pressure and pulse rate. A number of factors were incorporated into the experiment with the aim of increasing sensitivity above that of past research. In particular, the experiment's statistical power was increased using several techniques (e.g., large sample size and a repeated measures design). Also, intermittent exposure was used instead of continuous, and the conditions of exposure were optimised using field parameters specified by parametric resonance theory. To measure performance during exposure, the subjects' task on each of 150 trials was to decide which of two sequentially presented light flashes had the longer duration. The base duration was 50 ms and the alternative durations were 65, 100, or 125 ms. Both reaction time and percentage of correct responses were recorded for each subject. Total exposure time lasted approximately 9 minutes. Blood pressure and pulse were measured for a minimum of 5 minutes, both before and after exposure and sham exposure. The results showed that compared to sham exposure, real exposure decreased reaction time on the hardest level of the performance task. No reliable field-related effects were observed with percentage of correct decisions or the measures of cardiovascular response. The difficulty of making comparisons with similar studies was discussed along with the need for future magnetic field research to be designed with maximum experimental sensitivity in mind given that small effects are likely.
- ItemParkinson's disease : memory deficits : a dissertation presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Psychology at Massey University, New Zealand(Massey University, 1999) Whittington, Craig JParkinson's disease (PD) has long been thought of as a debilitating motor disease: only relatively recently has research focused on cognitive functioning. It is now widely accepted that memory processes are among the primary cognitive functions to deteriorate in PD. However, less is known about the role that task variables (e.g., difficulty) and participant characteristics (e.g., gender, disease progression) play in this relationship. In addition, few studies in the PD literature have looked at the important issues of statistical power and the magnitude of memory deficits. The present investigation addressed some of these concerns. The first stage involved conducting a power analysis, based on 48 studies, followed by a meta-analysis. The meta-analysis included 32 effect sizes from studies assessing recognition memory in PD. This analysis paved the way for a large-scale study examining recognition memory in 41 nondemented PD participants compared to 41 age- and education-matched healthy controls. Both verbal and nonverbal recognition tasks were specifically designed for this purpose, the latter employing two levels of difficulty. In addition, prospective memory (remembering to remember) was examined with two event-based tasks because no study to date has looked at this issue in PD. The results of the power analysis indicated that past research has typically had insufficient statistical power to detect all but the largest memory deficits. Integrating the data from many studies, the meta-analysis suggested that nondemented, medicated PD participants may suffer from small recognition deficits. Support was provided by the subsequent primary study. In addition, it was found that the progression of memory impairment operates in parallel with the progression of motor symptoms. Moreover, task demands interacted with disease stage, such that nonverbal recognition deficits were only seen in early-stage PD participants when the task was made more difficult. Conversely, advanced-stage participants produced deficits irrespective of the level of difficulty. With respect to prospective memory, only the advanced-stage participants showed clear evidence of memory impairment. The main outcome of this research is that recognition memory impairment does occur in PD. However, low levels of statistical power in previous research and moderating factors such as symptom severity and task difficulty have likely obscured true deficits.