A genome-wide scan of positive selection signature using Ovine Infinium® HD SNP BeadChip in two Romney lines, selected for resistance or resilience to nematodes

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dc.contributor.authorYan J
dc.contributor.authorDukkipati VSR
dc.contributor.authorBlair HT
dc.contributor.authorBiggs PJ
dc.contributor.authorHamie JC
dc.contributor.authorGreer A
dc.coverage.spatialTownsville, QLD, Australia
dc.date.available2017-07-03
dc.date.finish-date2017-07-05
dc.date.issued2017-07-03
dc.date.start-date2017-07-02
dc.description.abstractA study was undertaken to identify selection signatures associated with resistance to gastrointestinal nematodiasis in sheep. Ninety-three Romney sheep from two selection lines (resistant or resilient) were genotyped using the Ovine Infinium® HD SNP BeadChip, and extended haplotype homozygosity (EHH) and site-specific extended haplotype homozygosity (EHHS) analyses were undertaken. In total, 224 SNPs (147 in EHH and 77 in EHHS) were found to be significant (p <0.0001). Preliminary exploration of 10 SNPs found them to be located within two previously identified QTLs, namely LATRICH_2 and FECGEN, which were associated with nematode larval count and faecal egg count, respectively.
dc.identifier.citation2017
dc.identifier.elements-id375680
dc.identifier.harvestedMassey_Dark
dc.rightsThe Author(s)
dc.source22nd Conference of the Association for the Advancement of Animal Breeding and Genetics
dc.titleA genome-wide scan of positive selection signature using Ovine Infinium® HD SNP BeadChip in two Romney lines, selected for resistance or resilience to nematodes
dc.typeconference
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Agriculture & Environment
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