• Login
    View Item 
    •   Home
    • Massey Documents by Type
    • Theses and Dissertations
    • View Item
    •   Home
    • Massey Documents by Type
    • Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    A feasibility study to investigate the effectiveness and safety of an intermittent fasting diet for weight reduction in adults with Type 2 Diabetes treated with insulin : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Human Nutrition at Massey University, Albany, New Zealand

    Icon
    View/Open Full Text
    01_front.pdf (134.4Kb)
    02_whole.pdf (1.571Mb)
    Export to EndNote
    Abstract
    Background: Type 2 diabetes (T2DM) is the most common form of diabetes. Obesity is associated with both the development of T2DM and also the development of the complications of diabetes; increasing health care costs and morbidity and mortality. Weight loss and control of blood glucose levels should be managed with a tailored eating plan developed in negotiation between the person with diabetes and their health care team. It is essential that health care professionals are familiar with different strategies that achieve weight reduction, glycaemic and cardiovascular risk reduction goals. One emerging weight reduction strategy is fasting diets. There is currently a gap in the knowledge of whether fasting diets are an effective and safe weight reduction strategy for people with T2DM on insulin. Aim: To investigate the effectiveness and safety of an intermittent fasting diet (two day per week) as an alternative to standard dietary advice (portion control diet) for weight reduction in obese adults with insulin dependent T2DM attending a 12-week group based intervention at Waitemata District Health Board (DHB). Methods: Obese patients with T2DM treated with insulin who were attending Waitemata DHB Diabetes Service were recruited for this two arm open-label design intervention feasibility study. Both dietary strategies were implemented during a 12-week intervention at which participants received monthly dietitian-led group education and support. The intermittent fasting diet (IFD) intervention (n=8) investigated was a two day per week reduced energy intake (550-650kcal / 2300- 2700kJ per day) and five days’ usual intake making low fat choices. The portion control diet (PCD) was the comparison group (n=7) and focused on daily energy restriction through reduction in portion sizes and low fat food choices in line with current New Zealand dietary recommendations for management of T2DM. Results: Similar weight loss was achieved in both groups (IFD: 2.7 ± 3.0 kg, PCD: 1.7 ± 2.5 kg). This reduction was not significant between groups. There was a significant difference between groups in reduction in HbA1c. (P=0.003) (IFD: -11 mmol/mol, PCD: -3 mmol/mol). This decrease was significant in the IFD group only (P=0.018). Reported hypoglycaemic events were low in both groups (8 events in IFD; 21 events in PCD). Non-significant between group reductions in waist circumference (P=0.402), waist: height ratio (P=0.455), diastolic (P=0.189) and systolic blood pressure (P=0.443) were observed. Lipid profile remained stable in both groups. Conclusion: This feasibility study showed that an intermittent fasting diet can achieve similar weight loss to current standard practice dietary advice in people with T2DM. However, it is the significant reductions in HbA1c compared to a daily energy restriction diet over a three-month period seen in this study that warrant further investigation. With education from health care professionals and modification of insulin on pre-fasting and fasting day this diet may be followed safely and hypoglycaemia avoided or managed appropriately.
    Date
    2017
    Author
    Pace, Katrina Anne
    Rights
    The Author
    Publisher
    Massey University
    URI
    http://hdl.handle.net/10179/11000
    Collections
    • Theses and Dissertations
    Metadata
    Show full item record

    Copyright © Massey University
    | Contact Us | Feedback | Copyright Take Down Request | Massey University Privacy Statement
    DSpace software copyright © Duraspace
    v5.7-2020.1-beta1
     

     

    Tweets by @Massey_Research
    Information PagesContent PolicyDepositing content to MROCopyright and Access InformationDeposit LicenseDeposit License SummaryTheses FAQFile FormatsDoctoral Thesis Deposit

    Browse

    All of MROCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    Copyright © Massey University
    | Contact Us | Feedback | Copyright Take Down Request | Massey University Privacy Statement
    DSpace software copyright © Duraspace
    v5.7-2020.1-beta1