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dc.contributor.authorAllan, David Bruce
dc.date.accessioned2019-05-15T00:27:41Z
dc.date.available2019-05-15T00:27:41Z
dc.date.issued2018
dc.identifier.urihttp://hdl.handle.net/10179/14623
dc.descriptionFigures 2, 5, 6, 7, 8, 16 & 21 were removed for copyright reasons but may be accessed through their sources listed in the attached document "Copyrighted images".en
dc.description.abstractDrug delivery techniques are an integral component in modern medical practices. Numerous drugs have been designed to exploit drug delivery systems, primarily oral administration, as it is preferred by the public for treatment of animals and humans. Butorphanol is a commonly used opioid analgesic drug for pain relief in avian species. The pharmacokinetic reports on butorphanol suggest that it is metabolised and cleared from an avian body at a much faster rate when compared to mammals. A single intravenous injection of butorphanol at 2 mg/kg provides analgesia for only 2 hours. When given at higher doses, butorphanol starts to produce side effects such as hyperventilation, cardiac insufficiency, coma and death. Therefore, there is a need to develop a slow release drug delivery system for butorphanol which can prolong the duration of analgesia without the side effects.en_US
dc.language.isoenen_US
dc.publisherMassey Universityen_US
dc.rightsThe Authoren_US
dc.subjectColloids in medicineen_US
dc.subjectGels (Pharmacy)en_US
dc.subjectDrug delivery systemsen_US
dc.subjectDesignen_US
dc.subjectVeterinary drugsen_US
dc.subjectControlled releaseen
dc.subjectVeterinary drugsen
dc.subjectDosage formsen
dc.subjectAvian medicineen
dc.titleAn investigation into nanocellulose based hydrogels for analgesic treatment of avian species : thesis presented in partial fulfilment of the requirements for the degree of Master of Science, Chemistry, Massey University, Palmerston North, New Zealanden_US
dc.typeThesisen_US
thesis.degree.disciplineChemistryen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Science (MSc)en_US


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