A study on secreted proteins of Mycobacterium avium subspecies paratuberculosis vaccine strain 316F : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Massey University, Palmerston North, New Zealand
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Date
2010
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Massey University
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Abstract
Doctoral Student Citation:
Mycobacterium avium subspecies paratuberculosis strain316F is the organism in the live attenuated vaccine Neoparasec, which has been used to control Johne’s disease in cattle and sheep. Ms Sriasih’s research focussed on the identification of secreted proteins of this organism, which may have application in the development of diagnostic tests for Johne’s disease. Her results have contributed to the general body information concerning the immunogenic proteins of the vaccine strain 316F. The genetic approach undertaken to search for novel secreted proteins has resulted in the identification and characterisation of an immunogenic glutamine binding protein.
[Abstract not able to be extracted from thesis.]
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Keywords
Neoparasec vaccine, Johne's disease, Binding proteins, Antibody responses