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dc.contributor.authorWang, Jingjing
dc.contributor.authorWang, Jingjing
dc.date.accessioned2011-12-07T03:26:53Z
dc.date.available2011-12-07T03:26:53Z
dc.date.issued2011
dc.identifier.urihttp://hdl.handle.net/10179/2900
dc.descriptionCIF files are on the disk with the hard copy
dc.description.abstractThe Suzuki-Miyaura coupling reaction is one of the most powerful methods for the construction of biaryls. The biaryl motif has great importance in pharmaceutical, agrichemical and material science industries, and is often axially chiral. The outcome of a Suzuki-Miyaura coupling reaction can be influenced by many factors, but the ligand plays the most vital role. A large number of ligands have been developed, including many chiral ligands for asymmetric reactions. While ligand design has focused on molecules containing either central or axial chirality, little has been focused on planar chiral ligands. In this project, three new ligands based on the [2.2]paracyclophane backbone have been designed, pseudo-ortho substituted monophosphines (L1 and L2), secondary phosphine oxide and arylindolyl phosphine ligands (L3 and L4). Unfortunately, similar analogues of L1 and L2 were reported before our results, and a synthesis route to the secondary phosphine oxide ligands was not achieved. The use of L1 in gold mediated cyclisation was investigated, which concluded that L1 was not suitable for this kind of reaction. However, arylindolyl phosphine ligands were prepared successfully, and produced promising preliminary results in achiral Suzuki-Miyaura coupling reactions. Interesting X-ray crystallography structure of brominated indole is discussed.en_US
dc.publisherMassey Universityen_US
dc.rightsThe Authoren_US
dc.subjectAsymmetric catalysisen_US
dc.subjectLigandsen_US
dc.subjectChiralityen_US
dc.subjectParacyclophanesen_US
dc.subjectBiarylsen_US
dc.subjectPhosphineen_US
dc.titleA study of new planar chiral monophosphine ligands based on [2.2]paracyclophane and their use in catalysis : Chemistry, Institute of Fundamental Sciences, Massey University : Masters thesis under the supervision of Dr. Gareth J. Rowlandsen_US
dc.typeThesisen_US
thesis.degree.disciplineChemistry
thesis.degree.grantorMassey University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (M.Sc.)


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