Risk Factors for Hospitalisation amongst Leptospirosis Patients in New Zealand

Simple item page
dc.citation.issue4
dc.citation.volume6
dc.contributor.authorSokolova M
dc.contributor.authorMarshall JC
dc.contributor.authorBenschop J
dc.contributor.editorFrean J
dc.coverage.spatialSwitzerland
dc.date.accessioned2023-11-17T02:15:11Z
dc.date.accessioned2023-11-20T01:37:47Z
dc.date.available2021-10-20
dc.date.available2023-11-17T02:15:11Z
dc.date.available2023-11-20T01:37:47Z
dc.date.issued2021-12
dc.description.abstractLeptospirosis is a neglected zoonotic disease that is widespread in tropical and subtropical regions such as Oceania, which includes New Zealand. The incidence rate of leptospirosis in New Zealand remains high in comparison to other high-income countries, with over half of the notified patients hospitalised, and the factors associated with hospitalisation are poorly understood. This study aimed to estimate the risk factors for hospitalisation amongst leptospirosis patients using passive surveillance data: notifications from 1 January 1999 to 31 December 2017 extracted from New Zealand's notifiable disease database. There were 771 hospitalised and 673 non-hospitalised patients. Multivariable logistic regression was used to identify risk factors. The year of notification was significantly and positively associated with hospitalisation, with adjusted (adj.) OR 1.03 (95% CI:1.01-1.05). Occupation was significantly associated with hospitalisation, with the adjusted odds of hospitalisation amongst dairy farmers notified with leptospirosis at adj. OR 1.44 (95% CI: 1.02-2.02) times the adjusted odds of hospitalisation amongst farmers that worked with other livestock. Seropositivity for Leptospira interrogans Copenhageni (adj. OR 5.96, 95% CI: 1.68-21.17) and Pomona (adj. OR 1.14, 95% CI: 0.74-1.74)) was more likely to result in hospitalisation when compared to Leptospira borgpetersenii Ballum (baseline). Seropositivity for Leptospira borgpetersenii Hardjo (adj. OR 0.71, 95% CI: 0.49-1.01) and Tarassovi (adj. OR 0.39, 95% CI: 0.23-0.66) was less likely to result in hospitalisation when compared to Ballum (baseline). All the estimates were additionally adjusted for the effect of sex, age, ethnicity, reported occupational exposure, geographical location, reported season, and deprivation status Although passive surveillance data has limitations we have been able to identify that the New Zealand dairy farming population may benefit from a targeted awareness campaign.
dc.description.confidentialfalse
dc.edition.editionDecember 2021
dc.format.pagination188-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/34698310
dc.identifier.citationSokolova M, Marshall JC, Benschop J. (2021). Risk Factors for Hospitalisation amongst Leptospirosis Patients in New Zealand.. Trop Med Infect Dis. 6. 4. (pp. 188-).
dc.identifier.doi10.3390/tropicalmed6040188
dc.identifier.eissn2414-6366
dc.identifier.elements-typejournal-article
dc.identifier.issn2414-6366
dc.identifier.numberARTN 188
dc.identifier.piitropicalmed6040188
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/69126
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/2414-6366/6/4/188
dc.relation.isPartOfTrop Med Infect Dis
dc.rights(c) 2021 The Author/s
dc.rightsCC BY
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectLeptospira spp.
dc.subjecthospitalisation
dc.subjectrisk factors
dc.subjectsurveillance data
dc.titleRisk Factors for Hospitalisation amongst Leptospirosis Patients in New Zealand
dc.typeJournal article
pubs.elements-id449226
pubs.organisational-groupOther
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Published version
Size:
6.12 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Articles