Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study

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dc.citation.issue1
dc.citation.volume12
dc.contributor.authorRöhr S
dc.contributor.authorPabst A
dc.contributor.authorRiedel-Heller SG
dc.contributor.authorJessen F
dc.contributor.authorTurana Y
dc.contributor.authorHandajani YS
dc.contributor.authorBrayne C
dc.contributor.authorMatthews FE
dc.contributor.authorStephan BCM
dc.contributor.authorLipton RB
dc.contributor.authorKatz MJ
dc.contributor.authorWang C
dc.contributor.authorGuerchet M
dc.contributor.authorPreux P-M
dc.contributor.authorMbelesso P
dc.contributor.authorRitchie K
dc.contributor.authorAncelin M-L
dc.contributor.authorCarrière I
dc.contributor.authorGuaita A
dc.contributor.authorDavin A
dc.contributor.authorVaccaro R
dc.contributor.authorKim KW
dc.contributor.authorHan JW
dc.contributor.authorSuh SW
dc.contributor.authorShahar S
dc.contributor.authorDin NC
dc.contributor.authorVanoh D
dc.contributor.authorvan Boxtel M
dc.contributor.authorKöhler S
dc.contributor.authorGanguli M
dc.contributor.authorJacobsen EP
dc.contributor.authorSnitz BE
dc.contributor.authorAnstey KJ
dc.contributor.authorCherbuin N
dc.contributor.authorKumagai S
dc.contributor.authorChen S
dc.contributor.authorNarazaki K
dc.contributor.authorNg TP
dc.contributor.authorGao Q
dc.contributor.authorGwee X
dc.contributor.authorBrodaty H
dc.contributor.authorKochan NA
dc.contributor.authorTrollor J
dc.contributor.authorLobo A
dc.contributor.authorLópez-Antón R
dc.contributor.authorSantabárbara J
dc.contributor.authorCrawford JD
dc.contributor.authorLipnicki DM
dc.contributor.authorSachdev PS
dc.contributor.authorfor Cohort Studies of Memory in an International Consortium (COSMIC)
dc.coverage.spatialEngland
dc.date.accessioned2024-01-05T01:43:32Z
dc.date.accessioned2024-07-25T06:50:08Z
dc.date.available2020-12-18
dc.date.available2024-01-05T01:43:32Z
dc.date.available2024-07-25T06:50:08Z
dc.date.issued2020-12-18
dc.description.abstractBackground Subjective cognitive decline (SCD) is recognized as a risk stage for Alzheimer’s disease (AD) and other dementias, but its prevalence is not well known. We aimed to use uniform criteria to better estimate SCD prevalence across international cohorts. Methods We combined individual participant data for 16 cohorts from 15 countries (members of the COSMIC consortium) and used qualitative and quantitative (Item Response Theory/IRT) harmonization techniques to estimate SCD prevalence. Results The sample comprised 39,387 cognitively unimpaired individuals above age 60. The prevalence of SCD across studies was around one quarter with both qualitative harmonization/QH (23.8%, 95%CI = 23.3–24.4%) and IRT (25.6%, 95%CI = 25.1–26.1%); however, prevalence estimates varied largely between studies (QH 6.1%, 95%CI = 5.1–7.0%, to 52.7%, 95%CI = 47.4–58.0%; IRT: 7.8%, 95%CI = 6.8–8.9%, to 52.7%, 95%CI = 47.4–58.0%). Across studies, SCD prevalence was higher in men than women, in lower levels of education, in Asian and Black African people compared to White people, in lower- and middle-income countries compared to high-income countries, and in studies conducted in later decades. Conclusions SCD is frequent in old age. Having a quarter of older individuals with SCD warrants further investigation of its significance, as a risk stage for AD and other dementias, and of ways to help individuals with SCD who seek medical advice. Moreover, a standardized instrument to measure SCD is needed to overcome the measurement variability currently dominant in the field.
dc.format.pagination167-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/33339532
dc.identifier.citationRöhr S, Pabst A, Riedel-Heller SG, Jessen F, Turana Y, Handajani YS, Brayne C, Matthews FE, Stephan BCM, Lipton RB, Katz MJ, Wang C, Guerchet M, Preux P-M, Mbelesso P, Ritchie K, Ancelin M-L, Carrière I, Guaita A, Davin A, Vaccaro R, Kim KW, Han JW, Suh SW, Shahar S, Din NC, Vanoh D, van Boxtel M, Köhler S, Ganguli M, Jacobsen EP, Snitz BE, Anstey KJ, Cherbuin N, Kumagai S, Chen S, Narazaki K, Ng TP, Gao Q, Gwee X, Brodaty H, Kochan NA, Trollor J, Lobo A, López-Antón R, Santabárbara J, Crawford JD, Lipnicki DM, Sachdev PS, for Cohort Studies of Memory in an International Consortium (COSMIC) . (2020). Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study.. Alzheimers Res Ther. 12. 1. (pp. 167-).
dc.identifier.doi10.1186/s13195-020-00734-y
dc.identifier.eissn1758-9193
dc.identifier.elements-typejournal-article
dc.identifier.issn1758-9193
dc.identifier.pii10.1186/s13195-020-00734-y
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70975
dc.languageeng
dc.publisherBioMed Central Ltd
dc.relation.isPartOfAlzheimers Res Ther
dc.rights(c) 2020 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCohort study
dc.subjectData harmonization
dc.subjectEpidemiology
dc.subjectIndividual participant data
dc.subjectPrevalence
dc.subjectSubjective cognitive decline
dc.subjectAging
dc.subjectCognitive Dysfunction
dc.subjectCohort Studies
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNeuropsychological Tests
dc.subjectPrevalence
dc.titleEstimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study
dc.typeJournal article
pubs.elements-id455064
pubs.organisational-groupOther
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