Magnetic resonance imaging shows spinal curvature in Chinook salmon (Oncorhynchus tshawytscha) is associated with chronic inflammation of peri-vertebral soft tissues.

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dc.citation.issue3
dc.citation.volume47
dc.contributor.authorLovett BA
dc.contributor.authorFirth EC
dc.contributor.authorPerrott MR
dc.contributor.authorMunday JS
dc.contributor.authorPontre BP
dc.contributor.authorLydon A-MP
dc.contributor.authorSymonds JE
dc.contributor.authorPreece MA
dc.contributor.authorHerbert NA
dc.coverage.spatialEngland
dc.date.accessioned2024-07-31T03:09:01Z
dc.date.available2024-07-31T03:09:01Z
dc.date.issued2024-03-01
dc.description.abstractChinook salmon (Oncorhynchus tshawytscha) farmed in New Zealand are known to develop abnormal spinal curvature late in seawater production. Its cause is presently unknown, but there is evidence to suggest a neuromuscular pathology. Using magnetic resonance imaging (MRI), we evaluated the relationship between soft tissue pathology and spinal curvature in farmed Chinook salmon. Regions of interest (ROIs) presenting as pathologic MRI signal hyper-intensity were identified from scans of 24 harvest-sized individuals: 13 with radiographically-detectable spinal curvature and 11 without. ROIs were excised from individuals using anatomical landmarks as reference points and histologically analysed. Pathologic MRI signal was observed more frequently in individuals with radiographic curvature (92%, nā€‰=ā€‰12) than those without (18%, nā€‰=ā€‰2), was localized to the peri-vertebral connective tissues and musculature, and presented as three forms: inflammation, fibrosis, or both. These pathologies are consistent with a chronic inflammatory process, such as that observed during recovery from a soft tissue injury, and suggest spinal curvature in farmed Chinook salmon may be associated with damage to and/or compromised integrity of the peri-vertebral soft tissues. Future research to ascertain the contributing factors is required.
dc.description.confidentialfalse
dc.edition.editionMarch 2024
dc.format.paginatione13900-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/38058214
dc.identifier.citationLovett BA, Firth EC, Perrott MR, Munday JS, Pontre BP, Lydon A-MP, Symonds JE, Preece MA, Herbert NA. (2024). Magnetic resonance imaging shows spinal curvature in Chinook salmon (Oncorhynchus tshawytscha) is associated with chronic inflammation of peri-vertebral soft tissues.. J Fish Dis. 47. 3. (pp. e13900-).
dc.identifier.doi10.1111/jfd.13900
dc.identifier.eissn1365-2761
dc.identifier.elements-typejournal-article
dc.identifier.issn0140-7775
dc.identifier.numbere13900
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71172
dc.languageeng
dc.publisherJohn Wiley and Sons, Inc.
dc.publisher.urihttps://onlinelibrary.wiley.com/doi/10.1111/jfd.13900
dc.relation.isPartOfJ Fish Dis
dc.rights(c) 2023 The Author/s
dc.rightsCC BY-NC-ND 4.0
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectChinook salmon
dc.subjectMRI
dc.subjectchronic inflammation
dc.subjectfinfish skeletal health
dc.subjectneuromuscular pathology
dc.subjectspinal curvature
dc.subjectHumans
dc.subjectAnimals
dc.subjectSalmon
dc.subjectFish Diseases
dc.subjectSpine
dc.subjectSpinal Curvatures
dc.subjectInflammation
dc.titleMagnetic resonance imaging shows spinal curvature in Chinook salmon (Oncorhynchus tshawytscha) is associated with chronic inflammation of peri-vertebral soft tissues.
dc.typeJournal article
pubs.elements-id485145
pubs.organisational-groupOther
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