Acute effects of whey protein, alone and mixed with other macronutrients, on blood pressure and heart rate in older men

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dc.citation.issue1
dc.citation.volume22
dc.contributor.authorOberoi A
dc.contributor.authorGiezenaar C
dc.contributor.authorLange K
dc.contributor.authorJones KL
dc.contributor.authorHorowitz M
dc.contributor.authorChapman I
dc.contributor.authorSoenen S
dc.coverage.spatialEngland
dc.date.available2022-06-28
dc.date.available2022-06-09
dc.date.issued2022-12
dc.description.abstractBACKGROUND: Caloric supplements are increasingly used by older people, aiming to increase their daily protein intake. These high caloric drinks, rich in glucose and whey-protein in particular, may result in potential harmful decreases in blood pressure (BP). The effect of ingesting whey-protein with glucose and fat on BP is unknown. It has also been assumed that the maximum fall in systolic blood pressure occurs within 2 h of a meal. METHODS: This study aimed to determine in older men, the effects of whey-protein, alone and mixed with other macronutrients, on systolic (SBP) and diastolic (DBP) blood pressure and heart rate (HR) in older men for 3 h. Thirteen older men (age 75 ± 2yrs; body mass index (BMI) 25.6 ± 0.6 kg/m2) ingested a drink on separate study days: (i) 70 g whey-protein (P280); (ii) 14 g whey-protein, 28 g carbohydrate, 12.4 g fat (M280); (iii) 70 g whey-protein, 28 g carbohydrate, 12.4 g fat (M504); or (iv) a non-caloric control drink (C). RESULTS: SBP decreased after all three nutrient drinks compared to the C, with the greatest reduction after the M504 drink (P = 0.008). Maximal decreases in SBP (C: -14 ± 2 mmHg, P280: -22 ± 2 mmHg, M280: -22 ± 4 mmHg, M504: -24 ± 3 mmHg) occurred about 2 h after drink ingestion and this fall was sustained thereafter (120-180 min: P280 and M504 vs. C P < 0.05). Maximum DBP decreases and HR increases occurred after M504, with no differences between the effects of the P280 and M280 drinks. CONCLUSIONS: The effects of whey-protein containing drinks to lower BP and increase HR appear to be primarily dependent on their energy content rather than macronutrient composition and may persist for at least 3 h after ingestion,. Pure whey-protein drinks may represent the best approach to maximize protein intake without increasing the potential for deleterious BP falls in older people. TRIAL REGISTRATION: ACTRN12614000846628 , 14/03/2019.
dc.description.publication-statusPublished online
dc.format.extent535 - ?
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/35764960
dc.identifier10.1186/s12877-022-03213-1
dc.identifier.citationBMC Geriatr, 2022, 22 (1), pp. 535 - ?
dc.identifier.doi10.1186/s12877-022-03213-1
dc.identifier.eissn1471-2318
dc.identifier.elements-id454511
dc.identifier.harvestedMassey_Dark
dc.identifier.urihttps://hdl.handle.net/10179/17466
dc.languageeng
dc.publisherBioMed Central Ltd
dc.relation.isPartOfBMC Geriatr
dc.subjectAging
dc.subjectBlood pressure
dc.subjectDiet
dc.subjectHeart rate
dc.subjectWhey protein
dc.subjectAged
dc.subjectBlood Pressure
dc.subjectGlucose
dc.subjectHeart Rate
dc.subjectHumans
dc.subjectMale
dc.subjectNutrients
dc.subjectWhey Proteins
dc.subject.anzsrc1103 Clinical Sciences
dc.subject.anzsrc1106 Human Movement and Sports Sciences
dc.titleAcute effects of whey protein, alone and mixed with other macronutrients, on blood pressure and heart rate in older men
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Food and Advanced Technology
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