Genomic Variability of Canine Parvoviruses from a Selected Population of Dogs and Cats in Sri Lanka

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dc.citation.issue9
dc.citation.volume10
dc.contributor.authorJinadasa R
dc.contributor.authorGhosh S
dc.contributor.authorHills S
dc.contributor.authorPremalal T
dc.contributor.authorAtapattu U
dc.contributor.authorFuward M
dc.contributor.authorKalupahana W
dc.contributor.authorDunowska M
dc.contributor.editorGunn-Moore D
dc.contributor.editorAguiar DMD
dc.coverage.spatialSwitzerland
dc.date.accessioned2023-12-15T01:28:10Z
dc.date.accessioned2024-07-25T06:42:15Z
dc.date.available2021-08-29
dc.date.available2023-12-15T01:28:10Z
dc.date.available2024-07-25T06:42:15Z
dc.date.issued2021-08-29
dc.description.abstractThe aim of the study was to identify canine parvovirus type 2 (CPV-2) subtypes circulating among a selected population of domestic dogs and cats in Sri Lanka and to investigate the evolutionary patterns among Sri Lankan viruses in the context of contemporary global CPV-2 sequences. Altogether, 40/61 (65.6%) samples tested were positive for CPV-2 DNA, including 31/48 (64.6%) dogs and 9/13 (69%) cats. All three subtypes (CPV-2a, CPV-2b and CPV-2c) were detected, with CPV-2a being most common. International median joining haplotype network of 291 CPV-2 sequences suggested that there was little barrier for CPV-2 moving between different geographical regions worldwide, including Sri Lanka, and that there was no correlation between the genetic structure within the molecular network and the decade of sample collection. By contrast, there was correlation between CPV-2 subtype and genetic structure, both within the international network and within the network built from 31 Sri Lankan CPV-2 sequences only. The structure within the latter was not correlated with the location of the veterinary clinic where the samples were submitted, the age or species of the host. Altogether, we have shown that there is considerable variability of CPV-2 genotypes circulating in Sri Lanka, which is likely driven by both local evolution and introduction from other countries. The similarity of CPV-2 obtained from cats and dogs suggests that cats may play a role in the epidemiology of CPV-2 in Sri Lanka.
dc.description.confidentialfalse
dc.edition.editionSeptember 2021
dc.format.pagination1102-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/34578133
dc.identifier.citationJinadasa R, Ghosh S, Hills S, Premalal T, Atapattu U, Fuward M, Kalupahana W, Dunowska M. (2021). Genomic Variability of Canine Parvoviruses from a Selected Population of Dogs and Cats in Sri Lanka.. Pathogens. 10. 9. (pp. 1102-).
dc.identifier.doi10.3390/pathogens10091102
dc.identifier.eissn2076-0817
dc.identifier.elements-typejournal-article
dc.identifier.issn2076-0817
dc.identifier.numberARTN 1102
dc.identifier.piipathogens10091102
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70716
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/2076-0817/10/9/1102
dc.relation.isPartOfPathogens
dc.rights(c) The author/sen
dc.rights.licenseCC BY 4.0en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectCPV-2
dc.subjectCPV-2 evolution
dc.subjectCPV-2 host
dc.subjectCPV-2 subtypes
dc.subjectSri Lanka
dc.subjectcanine parvovirus
dc.subjecthyplotype network
dc.subjectviral evolution
dc.titleGenomic Variability of Canine Parvoviruses from a Selected Population of Dogs and Cats in Sri Lanka
dc.typeJournal article
pubs.elements-id448527
pubs.organisational-groupOther
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