Risk of stomach cancer in Aotearoa/New Zealand: A Māori population based case-control study.

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dc.citation.issue7
dc.citation.volume12
dc.contributor.authorEllison-Loschmann L
dc.contributor.authorSporle A
dc.contributor.authorCorbin M
dc.contributor.authorCheng S
dc.contributor.authorHarawira P
dc.contributor.authorGray M
dc.contributor.authorWhaanga T
dc.contributor.authorGuilford P
dc.contributor.authorKoea J
dc.contributor.authorPearce N
dc.date.available2017-07-21
dc.date.available2017-07-03
dc.date.issued2017
dc.description.abstractMāori, the indigenous people of New Zealand, experience disproportionate rates of stomach cancer, compared to non-Māori. The overall aim of the study was to better understand the reasons for the considerable excess of stomach cancer in Māori and to identify priorities for prevention. Māori stomach cancer cases from the New Zealand Cancer Registry between 1 February 2009 and 31 October 2013 and Māori controls, randomly selected from the New Zealand electoral roll were matched by 5-year age bands to cases. Logistic regression was used to estimate odd ratios (OR) and 95% confidence intervals (CI) between exposures and stomach cancer risk. Post-stratification weighting of controls was used to account for differential non-response by deprivation category. The study comprised 165 cases and 480 controls. Nearly half (47.9%) of cases were of the diffuse subtype. There were differences in the distribution of risk factors between cases and controls. Of interest were the strong relationships seen with increased stomach risk and having >2 people sharing a bedroom in childhood (OR 3.30, 95%CI 1.95-5.59), testing for H pylori (OR 12.17, 95%CI 6.15-24.08), being an ex-smoker (OR 2.26, 95%CI 1.44-3.54) and exposure to environmental tobacco smoke in adulthood (OR 3.29, 95%CI 1.94-5.59). Some results were attenuated following post-stratification weighting. This is the first national study of stomach cancer in any indigenous population and the first Māori-only population-based study of stomach cancer undertaken in New Zealand. We emphasize caution in interpreting the findings given the possibility of selection bias. Population-level strategies to reduce the incidence of stomach cancer in Māori include expanding measures to screen and treat those infected with H pylori and a continued policy focus on reducing tobacco consumption and uptake.
dc.description.publication-statusPublished
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406643100047&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=c5bb3b2499afac691c2e3c1a83ef6fef
dc.identifierARTN e0181581
dc.identifier.citationPLOS ONE, 2017, 12 (7)
dc.identifier.doi10.1371/journal.pone.0181581
dc.identifier.elements-id365456
dc.identifier.harvestedMassey_Dark
dc.identifier.issn1932-6203
dc.relation.isPartOfPLOS ONE
dc.relation.urihttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181581
dc.rights© 2017 Ellison-Loschmann et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.titleRisk of stomach cancer in Aotearoa/New Zealand: A Māori population based case-control study.
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Health
pubs.organisational-group/Massey University/College of Health/Research Centre for Hauora and Health
pubs.organisational-group/Massey University/Other
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