A contemporary understanding of iron metabolism in active premenopausal females
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Date
2022
Open Access Location
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Frontiers Media S.A
Rights
CC BY 4.0
Abstract
Iron metabolism research in the past decade has identified menstrual blood loss as a key contributor to the prevalence of iron deficiency in premenopausal females. The reproductive hormones estrogen and progesterone influence iron regulation and contribute to variations in iron parameters throughout the menstrual cycle. Despite the high prevalence of iron deficiency in premenopausal females, scant research has investigated female-specific causes and treatments for iron deficiency. In this review, we provide a comprehensive discussion of factors that influence iron status in active premenopausal females, with a focus on the menstrual cycle. We also outline several practical guidelines for monitoring, diagnosing, and treating iron deficiency in premenopausal females. Finally, we highlight several areas for further research to enhance the understanding of iron metabolism in this at-risk population.
Description
© 2022 The Author/s
Keywords
hepcidin, iron regulation, iron status, menstrual cycle, menstruation
Citation
Badenhorst CE, Forsyth AK, Govus AD. (2022). A contemporary understanding of iron metabolism in active premenopausal females.. Front Sports Act Living. 4. (pp. 903937-).