Bioprospecting soil metagenomes for potential new antibiotics : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, Albany, New Zealand

Simple item page
dc.contributor.authorHong, Kelly
dc.date.accessioned2018-05-03T03:54:46Z
dc.date.available2018-05-03T03:54:46Z
dc.date.issued2017
dc.description.abstractMany soil-dwelling microbes have the natural capacity to produce toxic compounds that inhibit growth of competing bacteria; most traditional antibiotics have been derived from small molecules made by such soil-based microorganisms, of which only a small fraction can be grown in the laboratory. Since techniques that require culturing of these microbes in the lab have been the starting point for studying them in the past, our knowledge of the uncultured majority remains limited. Functional metagenomics is a method that circumvents the need for culturing, and thus has the potential to revel a yet untapped reservoir of antibacterial compounds. Here we present a potential application of functional metagenomics using genes isolated from soil microbes that employs high throughput sequencing to identify microbial genes encoding novel compounds that inhibit bacterial growth.en
dc.identifier.urihttp://hdl.handle.net/10179/13306
dc.language.isoenen_US
dc.publisherMassey Universityen
dc.rightsThe Authoren
dc.subjectMetagenomicsen_US
dc.subjectMicrobial genomicsen_US
dc.subjectSoil microbiologyen_US
dc.titleBioprospecting soil metagenomes for potential new antibiotics : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, Albany, New Zealanden_US
massey.contributor.authorHong, Kelly
thesis.degree.disciplineGeneticsen_US
thesis.degree.grantorMassey Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Science (MSc)en_US
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
01_front.pdf
Size:
97.27 KB
Format:
Adobe Portable Document Format
Description:
Download
Thumbnail Image
Name:
02_whole.pdf
Size:
1.3 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
3.32 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Theses and Dissertations