Genetic studies of a darkening of the dorsal coat in agouti mice : a thesis ... for the degree of Master of Agricultural Science

Abstract

It is the candidate's contention that an understanding of the mechanisms of gene action and interaction at the physiological level, is a necessary basis for a fuller understanding of the principles and problems of animal breeding. On this point, Rae (1958) states ... "population genetics deals essentially with genes and final phenotypes, but has little to say about the vast developmental gap between the two". However, opportunities for physiological studies of simple Mendelian traits in farm livestock are few and far between, while the expense of such studies is normally prohibitive. Consequently, physiological genetic studies are normally carried out on small animals, especially the mouse. Gruneburg (1952) has reviewed the use that has been made of this mammal for genetic studies of all types. [FROM INTRODUCTION]