Bone health among premenopausal female alcoholics: A pilot study

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dc.citation.issue1
dc.citation.volume7
dc.contributor.authorClynes MA
dc.contributor.authorWyawahare P
dc.contributor.authorRobinson G
dc.contributor.authorDenison HJ
dc.contributor.authorEvans G
dc.contributor.authorGilmour M
dc.contributor.authorDennison EM
dc.date.available2014-01-27
dc.date.issued2014-01-27
dc.description.abstractWe report a pilot study of bone health of alcohol dependent women. Women admitted to an alcohol-withdrawal unit (cases) and a convenience sample of controls (nursing staff) were recruited and asked to complete a lifestyle questionnaire before undergoing heel ultrasound measurements. Fasting blood samples were obtained on the day of admission (day 1) and at 5 days. Bone turnover markers (P1NP and CTX) and vitamin D levels were measured in a subset of the alcohol dependent population. Cases were less physically active than controls. Alcoholic women had lower heel ultrasound derived Stiffness Index scores [mean 85.2 (17.6)] compared with controls [mean 95.5 (18.7)] (p=0.07). P1NP rose significantly over the detoxification programme [day 1: 28.35 ng/l (12.25); day 5: 34.19 ng/l (13.16), p=0.003] but CTX change was not significant. Lifestyle factors associated with poor bone health are prevalent in female alcoholics. Significant increase in bone formation was observed 5 days after alcohol withdrawal.
dc.description.publication-statusPublished
dc.format.extent14 - 18
dc.identifier.citationOpen Bone Journal, 2014, 7 (1), pp. 14 - 18
dc.identifier.doi10.2174/1876525401507010014
dc.identifier.eissn1876-5254
dc.identifier.elements-id380350
dc.identifier.harvestedMassey_Dark
dc.relation.isPartOfOpen Bone Journal
dc.rightsArticles are licensed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) (https://creativecommons.org/licenses/by/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, ensuring that the work is properly cited.
dc.titleBone health among premenopausal female alcoholics: A pilot study
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Health
pubs.organisational-group/Massey University/College of Health/Research Centre for Hauora and Health
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