Gender-specific design and effectiveness of non-pharmacological interventions against cognitive decline and dementia–protocol for a systematic review and meta-analysis

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dc.citation.issue8
dc.citation.volume16
dc.contributor.authorZuelke AE
dc.contributor.authorRiedel-Heller SG
dc.contributor.authorWittmann F
dc.contributor.authorPabst A
dc.contributor.authorRoehr S
dc.contributor.authorLuppa M
dc.coverage.spatialUnited States
dc.date.accessioned2024-01-07T22:27:01Z
dc.date.accessioned2024-07-25T06:38:25Z
dc.date.available2021-08-27
dc.date.available2024-01-07T22:27:01Z
dc.date.available2024-07-25T06:38:25Z
dc.date.issued2021-08-27
dc.description.abstractIntroduction Dementia is a public health priority with projected increases in the number of people living with dementia worldwide. Prevention constitutes a promising strategy to counter the dementia epidemic, and an increasing number of lifestyle interventions has been launched aiming at reducing risk of cognitive decline and dementia. Gender differences regarding various modifiable risk factors for dementia have been reported, however, evidence on gender-specific design and effectiveness of lifestyle trials is lacking. Therefore, we aim to systematically review evidence on gender-specific design and effectiveness of trials targeting cognitive decline and dementia. Methods and analysis We will conduct a systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Databases MEDLINE (PubMed interface), PsycINFO, Web of Science Core Collection, Cochrane Central Register of Controlled Trials (CENTRAL) and ALOIS will be searched for eligible studies using a predefined strategy, complemented by searches in clinical trials registers and Google for grey literature. Studies assessing cognitive function (overall measure or specific subdomains) as outcome in dementia-free adults will be included, with analyses stratified by level of cognitive functioning at baseline: a) cognitively healthy b) subjective cognitive decline 3) mild cognitive impairment. Two reviewers will independently evaluate eligible studies, extract data and determine methodological quality using the Scottish Intercollegiate Guidelines Network (SIGN)-criteria. If sufficient data with regards to quality and quantity are available, a meta-analysis will be conducted. Ethics and dissemination No ethical approval will be required as no primary data will be collected. PROSPERO registration number CRD42021235281.
dc.format.paginatione0256826-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/34449834
dc.identifier.citationZuelke AE, Riedel-Heller SG, Wittmann F, Pabst A, Roehr S, Luppa M. (2021). Gender-specific design and effectiveness of non-pharmacological interventions against cognitive decline and dementia-protocol for a systematic review and meta-analysis.. PLoS One. 16. 8. (pp. e0256826-).
dc.identifier.doi10.1371/journal.pone.0256826
dc.identifier.eissn1932-6203
dc.identifier.elements-typejournal-article
dc.identifier.issn1932-6203
dc.identifier.piiPONE-D-21-08933
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70596
dc.languageeng
dc.publisherPublic Library of Science (PLoS)
dc.relation.isPartOfPLoS One
dc.rights(c) 2021 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectAlzheimer Disease
dc.subjectCognition
dc.subjectCognitive Dysfunction
dc.subjectDementia
dc.subjectFemale
dc.subjectGuidelines as Topic
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectRandomized Controlled Trials as Topic
dc.subjectRisk Factors
dc.subjectRisk Reduction Behavior
dc.subjectSex Characteristics
dc.titleGender-specific design and effectiveness of non-pharmacological interventions against cognitive decline and dementia–protocol for a systematic review and meta-analysis
dc.typeJournal article
pubs.elements-id454998
pubs.organisational-groupOther
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