Benchmarking total hip replacement constructs using noninferiority analysis: the New Zealand joint registry study.

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dc.citation.issue1
dc.citation.volume22
dc.contributor.authorWyatt M
dc.contributor.authorFrampton C
dc.contributor.authorWhitehouse M
dc.contributor.authorDeere K
dc.contributor.authorSayers A
dc.contributor.authorKieser D
dc.coverage.spatialEngland
dc.date.accessioned2023-08-11T01:17:31Z
dc.date.accessioned2023-09-04T01:41:09Z
dc.date.available2021-08-21
dc.date.available2023-08-11T01:17:31Z
dc.date.available2023-09-04T01:41:09Z
dc.date.issued2021
dc.date.updated2023-08-10T23:50:33Z
dc.description.abstractBACKGROUND: The aim of this study was to compare the relative performance of total hip replacement constructs and discern if there is substantial variability in performance in currently commonly used prostheses in the New Zealand Joint Registry (NZJR) using a noninferiority analysis. METHODS: All patients who underwent a primary total hip replacement (THR) registered in the NZJR between 1st January 1999 to June 2020 were identified. Using a noninferiority analysis, the performance of hip prostheses were compared with the best performing contemporary construct. Construct failure was estimated using the 1-Kaplan Meier survival function method to estimate net failure. The difference in failure between the contemporary benchmark and other constructs was examined. RESULTS: In total 135,432 THR were recorded comprising 1035 different THR constructs. Notably 328 constructs were used just once. Forty-eight constructs (62,251 THR) had > 500 procedures at risk at 3 years post-primary of which 28 were inferior by at least 20% relative risk of which, 10 were inferior by at least 100% relative risk. Sixteen constructs were identified with > 500 procedures at risk at 10 years with 9 inferior by at least 20%, of which one was inferior by > 100% relative risk. There were fewer constructs noninferior to the best practice benchmark when we performed analysis by gender. In females at 10 years, from 5 constructs with > 500 constructs at risk, 2 were inferior at the 20% margin. In males at 10 years, there were only 2 eligible constructs of which one was inferior at the 20% margin. CONCLUSIONS: We discerned that there is substantial variability in construct performance and at most time points, just over half of constructs are inferior to the best performing construct by at least 20%. These results can facilitate informed decision-making when considering THR surgery.
dc.format.extent719-
dc.identifierARTN 719
dc.identifier10.1186/s12891-021-04602-0
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/34419036
dc.identifier.citationWyatt M, Frampton C, Whitehouse M, Deere K, Sayers A, Kieser D. (2021). Benchmarking total hip replacement constructs using noninferiority analysis: the New Zealand joint registry study.. BMC Musculoskelet Disord. 22. 1. (pp. 719-).
dc.identifier.doi10.1186/s12891-021-04602-0
dc.identifier.eissn1471-2474
dc.identifier.elements-typejournal-article
dc.identifier.harvestedMassey_Dark
dc.identifier.issn1471-2474
dc.identifier.urihttp://hdl.handle.net/10179/19928
dc.languageeng
dc.publisherBioMed Central Ltd
dc.relation.isPartOfBMC Musculoskelet Disord
dc.rights© The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.subjectBenchmarking
dc.subjectNoninferiority analysis
dc.subjectTotal hip replacement
dc.subjectArthroplasty, Replacement, Hip
dc.subjectBenchmarking
dc.subjectFemale
dc.subjectHip Prosthesis
dc.subjectHumans
dc.subjectMale
dc.subjectNew Zealand
dc.subjectRegistries
dc.titleBenchmarking total hip replacement constructs using noninferiority analysis: the New Zealand joint registry study.
dc.typeJournal article
pubs.elements-id448199
pubs.organisational-groupOther
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