The epidemiology of AmpC-producing Escherichia coli isolated from dairy cattle faeces on pasture-fed farms.

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dc.citation.issue10
dc.citation.volume70
dc.contributor.authorBurgess SA
dc.contributor.authorCookson AL
dc.contributor.authorBrousse L
dc.contributor.authorOrtolani E
dc.contributor.authorBenschop J
dc.contributor.authorAkhter R
dc.contributor.authorBrightwell G
dc.contributor.authorMcDougall S
dc.date.available2021
dc.date.issued2021-10
dc.descriptionRead and publish agreement 2022
dc.description.abstractIntroduction. Antibiotic use, particularly amoxicillin-clavulanic acid in dairy farming, has been associated with an increased incidence of AmpC-hyperproducing Escherichia coli.Gap statement. There is limited information on the incidence of AmpC-hyperproducing E. coli from seasonal pasture-fed dairy farms.Aim. We undertook a New Zealand wide cross-sectional study to determine the prevalence of AmpC-producing E. coli carried by dairy cattle.Methodology. Paddock faeces were sampled from twenty-six dairy farms and were processed for the selective growth of both extended-spectrum beta-lactamase (ESBL)- and AmpC-producing E. coli. Whole genome sequence analysis was carried out on 35 AmpC-producing E. coli.Results. No ESBL- or plasmid mediated AmpC-producing E. coli were detected, but seven farms were positive for chromosomal mediated AmpC-hyperproducing E. coli. These seven farms were associated with a higher usage of injectable amoxicillin antibiotics. Whole genome sequence analysis of the AmpC-producing E. coli demonstrated that the same strain (<3 SNPs difference) of E. coli ST5729 was shared between cows on a single farm. Similarly, the same strain (≤15 SNPs difference) of E. coli ST8977 was shared across two farms (separated by approximately 425 km).Conclusion. These results infer that both cow-to-cow and farm-to-farm transmission of AmpC-producing E. coli has occurred.
dc.description.publication-statusPublished
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000718022100020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=c5bb3b2499afac691c2e3c1a83ef6fef
dc.identifierARTN 001447
dc.identifier.citationJOURNAL OF MEDICAL MICROBIOLOGY, 2021, 70 (10)
dc.identifier.doi10.1099/jmm.0.001447
dc.identifier.eissn1473-5644
dc.identifier.elements-id449162
dc.identifier.harvestedMassey_Dark
dc.identifier.issn0022-2615
dc.relation.isPartOfJOURNAL OF MEDICAL MICROBIOLOGY
dc.rightsCC BY 4.0
dc.subjectantimicrobial resistance
dc.subjectAmpC
dc.subjectdairy
dc.subjectEscherichia coli
dc.subject.anzsrc06 Biological Sciences
dc.subject.anzsrc07 Agricultural and Veterinary Sciences
dc.subject.anzsrc11 Medical and Health Sciences
dc.titleThe epidemiology of AmpC-producing Escherichia coli isolated from dairy cattle faeces on pasture-fed farms.
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Veterinary Science
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