Candidate gene search for milk production and composition, milk coagulation properties, and milk protein profile in dairy sheep from a New Zealand flock

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dc.citation.issue1
dc.citation.volume36
dc.contributor.authorMarshall AC
dc.contributor.authorLopez-Villalobos N
dc.contributor.authorVigolo V
dc.contributor.authorMarchi MD
dc.contributor.authorLoveday SM
dc.contributor.authorWeeks M
dc.contributor.authorMcNabb W
dc.date.accessioned2025-08-03T23:55:36Z
dc.date.available2025-08-03T23:55:36Z
dc.date.issued2025-07-11
dc.description.abstractThe objective of this study was to perform genome-wide association analysis and thus search for candidate genes for milk production and composition, milk coagulation properties (MCP), and milk protein profile in dairy sheep from a New Zealand flock. After quality control, 45,801 single nucleotide polymorphisms (SNPs) were included in the analysis, 147 ewes, and 470 individual records. A total of 87 SNPs and 55 candidate genes were found across Ovis aries autosomes (OAR) 2, 3, 6, 16, 18, 20, 25, and 26. Of particular importance, were the candidate genes PDZRN4 for milk yield, and BMP2K for contents of αs1- and αs2-caseins. No SNPs were found in the casein genes, LALBA or PAEP. Only one SNP was significant for MCP, and overall, the genetic architecture of MCP was similar to that of ratio of casein to calcium, pH, lactose, and the ratio of casein to protein. Further studies with larger flocks and with genomic imputation are required to validate the findings of this study before incorporating markers or genes into breeding programmes.
dc.description.confidentialfalse
dc.identifier.citationMarshall AC, Lopez-Villalobos N, Vigolo V, Marchi MD, Loveday SM, Weeks M, McNabb W. (2025). Candidate gene search for milk production and composition, milk coagulation properties, and milk protein profile in dairy sheep from a New Zealand flock. Animal Biotechnology. 36. 1.
dc.identifier.doi10.1080/10495398.2025.2516688
dc.identifier.eissn1532-2378
dc.identifier.elements-typejournal-article
dc.identifier.issn1049-5398
dc.identifier.number2516688
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/73272
dc.languageEnglish
dc.publisherTaylor and Francis Group
dc.publisher.urihttps://www.tandfonline.com/doi/full/10.1080/10495398.2025.2516688
dc.relation.isPartOfAnimal Biotechnology
dc.rights(c) The author/sen
dc.rights.licenseCC BY-NCen
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectSheep milk
dc.subjectdairy sheep
dc.subjectmilk production
dc.subjectmilk composition
dc.subjectprotein profile
dc.subjectgenome-wide association
dc.titleCandidate gene search for milk production and composition, milk coagulation properties, and milk protein profile in dairy sheep from a New Zealand flock
dc.typeJournal article
pubs.elements-id501708
pubs.organisational-groupOther
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