Comparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila.

dc.citation.volume2023
dc.contributor.authorHawley HR
dc.contributor.authorRoberts CJ
dc.contributor.authorFitzsimons HL
dc.coverage.spatialUnited States
dc.date.accessioned2024-07-23T02:38:13Z
dc.date.available2024-07-23T02:38:13Z
dc.date.issued2023-06-30
dc.description.abstractSpatial and temporal control of gene expression in Drosophila is essential in elucidating gene function. Spatial control is facilitated by the UAS/GAL4 system, and this can be coupled with additional adaptations for precise temporal control and fine tuning of gene expression levels. Here we directly compare the level of pan-neuronal transgene expression governed by nSyb-GAL4 and elav-GAL4, as well as mushroom body-specific expression alongside OK107-GAL4. We also compare the temporal modulation of gene expression in neurons with the auxin-inducible gene expression system (AGES) and temporal and regional gene expression targeting (TARGET) systems.
dc.description.confidentialfalse
dc.edition.edition2023
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37396791
dc.identifier.citationHawley HR, Roberts CJ, Fitzsimons HL. (2023). Comparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila.. MicroPubl Biol. 2023.
dc.identifier.doi10.17912/micropub.biology.000885
dc.identifier.eissn2578-9430
dc.identifier.elements-typejournal-article
dc.identifier.issn2578-9430
dc.identifier.number000885
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70280
dc.languageeng
dc.publisherCaltech Library
dc.publisher.urihttps://www.micropublication.org/journals/biology/micropub-biology-000885
dc.relation.isPartOfMicroPubl Biol
dc.rights(c) 2023 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleComparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila.
dc.typeJournal article
pubs.elements-id462442
pubs.organisational-groupOther
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