Genetic characterization of equid herpesvirus type 1 from cases of abortion in Poland.

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dc.citation.issue8
dc.citation.volume162
dc.contributor.authorStasiak K
dc.contributor.authorDunowska M
dc.contributor.authorHills SF
dc.contributor.authorRola J
dc.date.available2017-08
dc.date.available2017-04-07
dc.date.issued2017-08
dc.description.abstractEquid herpesvirus type 1 (EHV-1) is a common viral infection associated with varied clinical outcomes including respiratory disease, abortion and neurological disease. We have characterized EHV-1 sequences (n = 38) obtained from cases of equine abortion in Poland between 1999 and 2016, based on sequencing of PCR products from open reading frames (ORF) 30 and 68 of the EHV-1 genome. The majority (81.6%) of sequences were not classified into any of the previously described groups based on the ORF68 sequence. The remaining sequences belonged to ORF68 group III (7.9%) or IV (10.5%). A haplotype network analysis did not show any obvious structure within networks of local Polish sequences, nor within a global network of 215 EHV-1 sequences when these networks were coloured based on the geographical origin of viruses or date of detection. Our data suggest that ORF68 does not provide a reliable molecular marker for epidemiological studies of EHV-1, at least in a global sense. Its usefulness to aid local investigations of individual outbreaks remains to be established. All but two Polish EHV-1 sequences belonged to the ORF30 N752 genotype. The two ORF30 D752 viruses were obtained from abortion cases in 2009 and 2010. Hence, abortion cases that occurred in Poland between 1999 and 2016 were caused predominantly by EHV-1 with the ORF30 N752 genotype, with no indication of an increase in the prevalence of the ORF30 D752 variant.
dc.description.publication-statusPublished
dc.format.extent2329 - 2335
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000405497700017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=c5bb3b2499afac691c2e3c1a83ef6fef
dc.identifier.citationARCHIVES OF VIROLOGY, 2017, 162 (8), pp. 2329 - 2335
dc.identifier.doi10.1007/s00705-017-3376-3
dc.identifier.eissn1432-8798
dc.identifier.elements-id347811
dc.identifier.harvestedMassey_Dark
dc.identifier.issn0304-8608
dc.relation.isPartOfARCHIVES OF VIROLOGY
dc.relation.urihttps://link.springer.com/article/10.1007/s00705-017-3376-3
dc.rightsThe Author(s) 2017. This article is an open access publication
dc.subject.anzsrc06 Biological Sciences
dc.subject.anzsrc07 Agricultural and Veterinary Sciences
dc.subject.anzsrc11 Medical and Health Sciences
dc.titleGenetic characterization of equid herpesvirus type 1 from cases of abortion in Poland.
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Natural Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Veterinary Science
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