Osteoporosis is the cause of spontaneous humeral fracture in dairy cows from New Zealand.

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dc.citation.issue1
dc.citation.volume60
dc.contributor.authorWehrle-Martinez A
dc.contributor.authorLawrence K
dc.contributor.authorBack PJ
dc.contributor.authorRogers CW
dc.contributor.authorGibson M
dc.contributor.authorDittmer KE
dc.coverage.spatialUnited States
dc.date.available2023-01
dc.date.issued2023-01
dc.descriptionWehrle-Martinez, A., Lawrence, K., Back P.J., Rogers, C.W., Gibson, M., Dittmer, K.E., “Osteoporosis is the cause of spontaneous humeral fracture in dairy cows from New Zealand” First Published in “Veterinary Pathology” Vol. 60(1) 88-100, 2023, CC BY. https://doi.org/10.1177/03009858221122500
dc.description.abstractOutbreaks of humeral fractures in dairy cows have been reported in New Zealand for several years. Gross, histologic, and histomorphometric findings in the humerus from primiparous cows with spontaneous humeral fracture were compared to age-matched control cows. Affected cows had a complete nonarticular spiral fracture of the humerus. Histologically affected humeri had a thicker growth plate with abnormal architecture, thinner cortex with increased abnormal resorption, increased resorption in the distal humerus, decreased trabecular density, abnormal trabecular architecture, presence of growth arrest lines and woven bone formation. Histomorphometry showed reduction in bone volume, trabecular perimeter, and trabecular width. Cows grazed on fodder beet had thicker growth plates with an abnormal appearance compared with cows grazed on pasture, and cows with low/marginal liver copper concentration had more resorption cavities in the distal humerus and thinner cortical bone compared with cows with adequate liver copper concentration. Decreased trabecular density (OR = 249.5), abnormal cortical resorption (OR = 54.2), presence of woven bone formation in the proximal metaphysis (OR = 37.2), and the number of resorption cavities in the distal humerus were significantly associated with a high probability of fracture. Ribs had enlargement of the costochondral junction with fractures in different stages of healing. Histology of the ribs revealed abnormal growth plate appearance, presence of fracture lines, callus tissue, fibrosis, and microfractures. Cows with humeral fracture have osteoporosis due to decreased bone formation and increased bone resorption, likely associated with inadequate feed quality and perhaps copper deficiency leading to a reduction in bone strength and fracture.
dc.description.publication-statusPublished
dc.format.extent88 - 100
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/36112824
dc.identifier.citationVet Pathol, 2023, 60 (1), pp. 88 - 100
dc.identifier.doi10.1177/03009858221122500
dc.identifier.eissn1544-2217
dc.identifier.elements-id456862
dc.identifier.harvestedMassey_Dark
dc.identifier.urihttps://hdl.handle.net/10179/18073
dc.languageeng
dc.relation.isPartOfVet Pathol
dc.subjectcopper
dc.subjectcows
dc.subjectfodder beet
dc.subjecthistology
dc.subjecthistomorphometry
dc.subjecthumeral fractures
dc.subjectosteoporosis
dc.subjectFemale
dc.subjectCattle
dc.subjectAnimals
dc.subjectNew Zealand
dc.subjectCopper
dc.subjectHumeral Fractures
dc.subjectHumerus
dc.subjectOsteoporosis
dc.subjectCattle Diseases
dc.subject.anzsrc0704 Fisheries Sciences
dc.subject.anzsrc0707 Veterinary Sciences
dc.titleOsteoporosis is the cause of spontaneous humeral fracture in dairy cows from New Zealand.
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Agriculture & Environment
pubs.organisational-group/Massey University/College of Sciences/School of Veterinary Science
pubs.organisational-group/Massey University/Other
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