Benchmarking total knee replacement constructs using noninferiority analysis: the New Zealand joint registry study

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dc.citation.issue1
dc.citation.volume22
dc.contributor.authorWyatt MC
dc.contributor.authorFrampton CF
dc.contributor.authorWhitehouse MR
dc.contributor.authorDeere KC
dc.contributor.authorSayers A
dc.contributor.authorKieser D
dc.coverage.spatialEngland
dc.date.accessioned2023-08-11T03:06:58Z
dc.date.accessioned2023-09-04T01:41:09Z
dc.date.available2021-08-23
dc.date.available2023-08-11T03:06:58Z
dc.date.available2023-09-04T01:41:09Z
dc.date.issued2021-08-23
dc.date.updated2023-08-10T23:41:18Z
dc.description.abstractBACKGROUND: The aim of this study was to compare the relative performance of total knee replacement constructs and discern if there is variability in performance in currently commonly used prostheses in the New Zealand Joint Registry (NZJR) using a noninferiority analysis. METHODS: All patients who underwent a primary total knee replacement (TKR) registered in the NZJR between 1st January 1999 to June 2020 were identified. Using a noninferiority analysis, the performance of total knee replacement prostheses were compared with the best performing contemporary construct. Construct all-cause revision rate was estimated using the 1-Kaplan Meier survival function method to estimate net failure. The difference in all-cause revision rates between the contemporary benchmark and all other constructs was tested. RESULTS: In total 110 183 TKR were recorded and 25 constructs (102 717 procedures) had > 500 procedures at risk at 3 years post-primary of which 5 were inferior by at least 20 % relative risk of which, one was inferior by at least 100 % relative risk. 14 constructs were identified with > 500 procedures at risk at 10 years with 5 inferior by at least 20 %, of which 2 were inferior by > 100 % relative risk. CONCLUSIONS: We discerned that there is great variability in construct performance and at all time points, greater than 25 % of constructs are inferior to the best performing construct by at least 20 %. These results can help inform patients, clinicians and health care funders when considering TKR surgery.
dc.format.extent721-
dc.identifier10.1186/s12891-021-04606-w
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/34425821
dc.identifier.citationWyatt MC, Frampton CF, Whitehouse MR, Deere KC, Sayers A, Kieser D. (2021). Benchmarking total knee replacement constructs using noninferiority analysis: the New Zealand joint registry study.. BMC Musculoskelet Disord. 22. 1. (pp. 721-).
dc.identifier.doi10.1186/s12891-021-04606-w
dc.identifier.eissn1471-2474
dc.identifier.elements-typejournal-article
dc.identifier.harvestedMassey_Dark
dc.identifier.issn1471-2474
dc.identifier.urihttp://hdl.handle.net/10179/19927
dc.languageeng
dc.publisherBioMed Central Ltd
dc.relation.isPartOfBMC Musculoskelet Disord
dc.rights© The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the dataen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.subjectBenchmarking
dc.subjectNoninferiority analysis
dc.subjectTotal knee replacement
dc.subjectArthroplasty, Replacement, Knee
dc.subjectArtificial Limbs
dc.subjectBenchmarking
dc.subjectHumans
dc.subjectNew Zealand
dc.subjectProsthesis Failure
dc.subjectRegistries
dc.subjectReoperation
dc.titleBenchmarking total knee replacement constructs using noninferiority analysis: the New Zealand joint registry study
dc.typeJournal article
pubs.elements-id448371
pubs.organisational-groupOther
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