Neurovascular coupling during dynamic upper body resistance exercise in healthy individuals.

Simple item page
dc.citation.volumeEarly View
dc.contributor.authorKorad S
dc.contributor.authorMündel T
dc.contributor.authorPerry BG
dc.contributor.editorOgoh S
dc.coverage.spatialEngland
dc.date.accessioned2024-10-15T22:00:32Z
dc.date.available2024-10-15T22:00:32Z
dc.date.issued2024-09-25
dc.description.abstractDuring unilateral static and rhythmic handgrip exercise, middle cerebral artery blood velocity (MCAv) increases in the contralateral side to the exercising limb. However, whether this neurovascular coupling-mediated increase in contralateral MCAv is apparent against a background of fluctuating perfusion pressure produced by dynamic resistance exercise (RE) is unclear. We examined the cerebral haemodynamic response to unilateral dynamic RE in 30 healthy individuals (female = 16, mean ± SD: age, 26 ± 6 years; height, 175 ± 10 cm; weight, 74 ± 15 kg; body mass index, 24 ± 5 kg m-2). Participants completed four sets of 10 paced repetitions (15 repetitions min-1) of unilateral bicep curl exercise at 60% of the predicted one-repetition maximum (7 ± 3 kg). Beat-to-beat blood pressure, bilateral MCAv and end-tidal carbon dioxide were measured throughout. One-way ANOVA was used to analyse cardiovascular variables and two-way ANOVA to analyse dependent cerebrovascular variables (side × sets, 2 × 5). A linear mixed model analysis was also performed to investigate the effects of end-tidal carbon dioxide and mean arterial blood pressure on MCAv. In comparison to baseline, within-exercise mean arterial blood pressure increased (P < 0.001) across the sets, whereas bilateral MCAv decreased (P < 0.001). However, no significant interaction effect was observed for any dependent variables (all P > 0.787). The linear mixed model revealed that end-tidal carbon dioxide had the greatest effect on MCAv (estimate = 1.019, t = 8.490, P < 0.001). No differences were seen in contralateral and ipsilateral MCAv during dynamic RE, suggesting that neurovascular coupling contributions during dynamic RE might be masked by other regulators, such as blood pressure.
dc.description.confidentialfalse
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/39320059
dc.identifier.citationKorad S, Mündel T, Perry BG. (2024). Neurovascular coupling during dynamic upper body resistance exercise in healthy individuals.. Exp Physiol. Early View.
dc.identifier.doi10.1113/EP091970
dc.identifier.eissn1469-445X
dc.identifier.elements-typejournal-article
dc.identifier.issn0958-0670
dc.identifier.numberEP091970
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71731
dc.languageeng
dc.publisherJohn Wiley and Sons on behalf of The Physiological Society
dc.publisher.urihttps://physoc.onlinelibrary.wiley.com/doi/10.1113/EP091970
dc.relation.isPartOfExp Physiol
dc.rights(c) The author/sen
dc.rights.licenseCC BYen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectmiddle cerebral artery blood velocity
dc.subjectneurovascular coupling
dc.subjectresistance exercise
dc.titleNeurovascular coupling during dynamic upper body resistance exercise in healthy individuals.
dc.typeJournal article
pubs.elements-id491701
pubs.organisational-groupCollege of Health
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Published version.pdf
Size:
835.05 KB
Format:
Adobe Portable Document Format
Description:
491701 PDF.pdf
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
9.22 KB
Format:
Plain Text
Description:
Download
Collections
Journal Articles