Gestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial

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dc.contributor.authorAmitrano F
dc.contributor.authorManerkar K
dc.contributor.authorAlsweiler JM
dc.contributor.authorConlon CA
dc.contributor.authorCrowther CA
dc.contributor.authorEdlin R
dc.contributor.authorHarding JE
dc.contributor.authorMcCowan LME
dc.contributor.authorMeyer MP
dc.contributor.authorRowan JA
dc.contributor.authorRush EC
dc.contributor.authorMcKinlay CJD
dc.date.accessioned2025-09-25T03:03:27Z
dc.date.available2025-09-25T03:03:27Z
dc.date.issued2025-09-05
dc.description.abstractObjective To assess the impact of gestational diabetes(GDM) detection thresholds on infant growth, nutrition, and neurodevelopment at 12-18 months. Design Prospective cohort study within the GEMS trial(ACTRN12615000290594), which randomized pregnant women to detection of GDM using lower or higher glycemic criteria. The main outcomes were overweight/rapid weight gain; food approach appetitive score; energy intake; cognitive z-score. Result Compared to control infants, those exposed to GDM detected and treated by higher criteria or by lower but not higher criteria that was untreated, were less likely to have increased overweight/rapid weight gain, possibly with lower energy intake. There were no important differences in appetite and cognition. Infants exposed to GDM by lower but not higher criteria that was treated were similar to controls. Conclusion Exposure to treated GDM or untreated GDM detected by lower but not higher criteria, was not associated with increased infant risk factors for obesity or adverse cognitive outcomes.
dc.description.confidentialfalse
dc.identifier.citationAmitrano F, Manerkar K, Alsweiler JM, Conlon CA, Crowther CA, Edlin R, Harding JE, McCowan LME, Meyer MP, Rowan JA, Rush EC, McKinlay CJD. (2025). Gestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial. Journal of Perinatology.
dc.identifier.doi10.1038/s41372-025-02406-x
dc.identifier.eissn1476-5543
dc.identifier.elements-typejournal-article
dc.identifier.issn0743-8346
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/73609
dc.languageEnglish
dc.publisherSpringer Nature Limited
dc.publisher.urihttp://nature.com/articles/s41372-025-02406-x
dc.relation.isPartOfJournal of Perinatology
dc.rights(c) 2025 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleGestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial
dc.typeJournal article
pubs.elements-id503237
pubs.organisational-groupOther
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