Glycan Utilisation and Function in the Microbiome of Weaning Infants

Simple item page
dc.citation.issue7
dc.citation.volume7
dc.contributor.authorMcKeen S
dc.contributor.authorYoung W
dc.contributor.authorFraser K
dc.contributor.authorRoy NC
dc.contributor.authorMcNabb WC
dc.coverage.spatialSwitzerland
dc.date.accessioned2024-10-17T22:45:03Z
dc.date.available2024-10-17T22:45:03Z
dc.date.issued2019-07-04
dc.description.abstractGlycans are present exogenously in the diet, expressed and secreted endogenously by host cells, and produced by microbes. All of these processes result in them being available to the gut microbiome, firmly placing glycans at the interface of diet-microbe-host interactions. The most dramatic shift in dietary sources of glycans occurs during the transition from the milk-based neonatal diet to the diverse omnivorous adult diet, and this has profound effects on the composition of the gut microbiome, gene expression by microbes and host cells, mucin composition, and immune development from innate towards adaptive responses. Understanding the glycan-mediated interactions occurring during this transitional window may inform dietary recommendations to support gut and immune development during a vulnerable age. This review aims to summarise the current state of knowledge on dietary glycan mediated changes that may occur in the infant gut microbiome and immune system during weaning.
dc.description.confidentialfalse
dc.edition.editionJuly 2019
dc.format.paginationE190-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/31277402
dc.identifier.citationMcKeen S, Young W, Fraser K, Roy NC, McNabb WC. (2019). Glycan Utilisation and Function in the Microbiome of Weaning Infants.. Microorganisms. 7. 7. (pp. E190-).
dc.identifier.doi10.3390/microorganisms7070190
dc.identifier.eissn2076-2607
dc.identifier.elements-typejournal-article
dc.identifier.issn2076-2607
dc.identifier.numberARTN 190
dc.identifier.piimicroorganisms7070190
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71753
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/2076-2607/7/7/190
dc.relation.isPartOfMicroorganisms
dc.rights(c) 2019 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectcomplementary feeding
dc.subjectglycobiology discipline
dc.subjectmicrobiome
dc.subjectpolysaccharides
dc.titleGlycan Utilisation and Function in the Microbiome of Weaning Infants
dc.typeJournal article
pubs.elements-id424725
pubs.organisational-groupOther
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