Bone quality changes as measured by Raman and FTIR spectroscopy in primiparous cows with humeral fracture from New Zealand.

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dc.citation.volume10
dc.contributor.authorWehrle-Martinez A
dc.contributor.authorWaterland MR
dc.contributor.authorNaffa R
dc.contributor.authorLawrence K
dc.contributor.authorBack PJ
dc.contributor.authorRogers CW
dc.contributor.authorDittmer K
dc.coverage.spatialSwitzerland
dc.date.available2023
dc.date.available2023-01-23
dc.date.issued2023
dc.description.abstractThe occurrence of spontaneous humeral fractures in primiparous dairy cows from New Zealand prompted the study of bone material from affected cows to further characterize this condition and to outline a likely pathogenesis. Previous studies indicate that these cows developed osteoporosis due to periods of suboptimal bone formation followed by increased bone resorption during the period of lactation complicated by copper deficiency. We hypothesized that there are significant differences in the chemical composition/bone quality in bones from cows with spontaneous humeral fracture compared to cows without humeral fractures. In this study, Raman and Fourier transform infrared spectroscopy band ratios were, for the first time, measured, calculated, and compared in bone samples from 67 primiparous dairy cows that suffered a spontaneous fracture of the humerus and 14 age-matched post-calving cows without humeral fractures. Affected bone showed a significantly reduced mineral/matrix ratio, increased bone remodeling, newer bone tissue with lower mineralization and, lower carbonate substitution, and reduced crystallinity. As such, is likely that these have detrimentally impacted bone quality and strength in affected cows.
dc.description.publication-statusPublished online
dc.format.extent1063427 - ?
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/36846251
dc.identifier.citationFront Vet Sci, 2023, 10 pp. 1063427 - ?
dc.identifier.doi10.3389/fvets.2023.1063427
dc.identifier.elements-id459968
dc.identifier.harvestedMassey_Dark
dc.identifier.issn2297-1769
dc.languageeng
dc.relation.isPartOfFront Vet Sci
dc.rights(c) The author/s CC BY 4.0
dc.subjectFTIR spectroscopy
dc.subjectRaman
dc.subjectband ratios
dc.subjectcows
dc.subjecthumeral fracture
dc.subjectosteoporosis
dc.subject.anzsrc0707 Veterinary Sciences
dc.titleBone quality changes as measured by Raman and FTIR spectroscopy in primiparous cows with humeral fracture from New Zealand.
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Agriculture & Environment
pubs.organisational-group/Massey University/College of Sciences/School of Veterinary Science
pubs.organisational-group/Massey University/Other
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