Effects of early postnatal life nutritional interventions on immune-microbiome interactions in the gastrointestinal tract and implications for brain development and function

Simple item page
dc.citation.volume13
dc.contributor.authorMullaney JA
dc.contributor.authorRoy NC
dc.contributor.authorHalliday C
dc.contributor.authorYoung W
dc.contributor.authorAltermann E
dc.contributor.authorKruger MC
dc.contributor.authorDilger RN
dc.contributor.authorMcNabb WC
dc.contributor.editorWang H
dc.coverage.spatialSwitzerland
dc.date.accessioned2023-07-16T21:25:06Z
dc.date.accessioned2023-09-04T01:40:43Z
dc.date.available2022-11-23
dc.date.available2023-07-16T21:25:06Z
dc.date.available2023-09-04T01:40:43Z
dc.date.issued2022-11-23
dc.date.updated2023-07-11T23:45:41Z
dc.descriptionThis is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
dc.description.abstractThe gastrointestinal (GI) microbiota has co-evolved with the host in an intricate relationship for mutual benefit, however, inappropriate development of this relationship can have detrimental effects. The developing GI microbiota plays a vital role during the first 1,000 days of postnatal life, during which occurs parallel development and maturation of the GI tract, immune system, and brain. Several factors such as mode of delivery, gestational age at birth, exposure to antibiotics, host genetics, and nutrition affect the establishment and resultant composition of the GI microbiota, and therefore play a role in shaping host development. Nutrition during the first 1,000 days is considered to have the most potential in shaping microbiota structure and function, influencing its interactions with the immune system in the GI tract and consequent impact on brain development. The importance of the microbiota-GI-brain (MGB) axis is also increasingly recognized for its importance in these developmental changes. This narrative review focuses on the importance of the GI microbiota and the impact of nutrition on MGB axis during the immune system and brain developmental period in early postnatal life of infants.
dc.description.confidentialfalse
dc.format.extent960492-
dc.identifier960492
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/36504799
dc.identifier.citationMullaney JA, Roy NC, Halliday C, Young W, Altermann E, Kruger MC, Dilger RN, McNabb WC. (2022). Effects of early postnatal life nutritional interventions on immune-microbiome interactions in the gastrointestinal tract and implications for brain development and function.. Front Microbiol. 13. (pp. 960492-).
dc.identifier.doi10.3389/fmicb.2022.960492
dc.identifier.eissn1664-302X
dc.identifier.elements-typejournal-article
dc.identifier.harvestedMassey_Dark
dc.identifier.issn1664-302X
dc.identifier.urihttp://hdl.handle.net/10179/19870
dc.languageeng
dc.publisherFrontiers Media S A
dc.publisher.urihttps://www.frontiersin.org/articles/10.3389/fmicb.2022.960492/full
dc.relation.isPartOfFront Microbiol
dc.rights(c) The author/s CC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectdiet
dc.subjectearly life
dc.subjectgastrointestinal microbiota
dc.subjectgastrointestinal-brain development
dc.subjectimmune development
dc.subjectmicrobiota-GI-brain axis
dc.titleEffects of early postnatal life nutritional interventions on immune-microbiome interactions in the gastrointestinal tract and implications for brain development and function
dc.typeJournal article
pubs.elements-id458541
pubs.organisational-groupOther
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
458541 PDF.pdf
Size:
611.2 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Articles