Physiological, psychological and functional changes with whole body vibration exercise in the frail elderly : a thesis presented in fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Sport & Exercise at Massey University, Wellington, New Zealand

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Background The frail elderly endure comprehensive reductions in health, function, independence, wellbeing and Quality of Life. Conventional training attenuates declines but is restricted by requisite intensities and supervisory-requirements. Whole Body Vibration (WBV) exercise presents as a safe and effective training-tool for the mobile elderly, yet a paucity of research exists on its application in the frail elderly, who could benefit most. Methods After pre-screening for contraindications, 117 male and female volunteers (82.5 ± 7.9 years) from residential-care-facilities were randomly allocated to Control (CON), Simulated-exercise (SIM) or WBV-exercise (WBV) groups. Continuing regular-care, WBV- and SIM-participants also underwent thrice-weekly exercise sessions for 16 weeks. Delivered by overload principle, WBV-training began with 5*1-min bouts of rotational-WBV at 6 Hz/2 mm (1:1min exercise:rest), progressing ad libitum to 10*1-min at up-to 26 Hz/4 mm, maintaining knee-flexion. Training for SIM-participants mimicked exercise stance and duration. Pre- and post-measures of function (Timed-Up-and-Go (TUG), Parallel Walk (PWT) and 10-m Timed-Walk tests), psychometrics (ABC-UK falls confidence, EURO-QoL-5-D and Barthel Index) and cardiovascular-health (Blood Pressures, resting Heartrate, Augmentation Index (AIx)) were completed up-to 12-months post-intervention. Twenty-participants (84.5 ± 1.7 years) from WBV- and SIM-groups underwent further bone-health assessments (serum Osteocalcin and Vitamin D, urinary Pyridinoline/Deoxypyridinoline, and Bone Mineral Density (BMD)). Results High levels of compliance and ease-of-use were reported, with no adverse-effects. Compared to baseline-levels, 8- and 16-weeks of WBV-training elicited clinically-important treatment-effects on participants’ functionality, psychometrics and cardiovascular-health. Notably, improvements of 7.3% and 14.9% were seen in TUG- and PWT-performance, respectively, whilst falls-confidence increased by 17.4% and AIx reduced by 23.3%. Many treatment-effects remained in-place up-to 12-months post-intervention. No treatment-effects were observed for BMD-levels, but beneficial treatment-effects were detected on osteocalcin levels. Findings showed low-level WBV-exercise to be an effective and easily-accessible exercise for the frail elderly. The exercise-intervention delivered sufficient-stimulus to significantly increase functionality, independence, confidence and Quality of Life. Furthermore, the novel vascular-health findings offer insight into the safe use of low-level WBV-exercise in patients with poor cardiovascular-health. Bone-deposition rates increased, albeit not sufficiently to enhance BMD-levels. However, the lack of adverse-effects suggest WBV-exercise is a safe and effective training-tool for this population when other training-goals are the focus.

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Appendix A: Published Methods Paper was removed for copyright reasons but may be accessed via https://doi.org/10.1016/j.cct.2015.08.008

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