Depression, anxiety and quality of life in subjects with atopic eczema in a population-based cross-sectional study in Germany

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dc.citation.issue4
dc.citation.volume34
dc.contributor.authorTreudler R
dc.contributor.authorZeynalova S
dc.contributor.authorRiedel-Heller SG
dc.contributor.authorZuelke AE
dc.contributor.authorRoehr S
dc.contributor.authorHinz A
dc.contributor.authorGlaesmer H
dc.contributor.authorKage P
dc.contributor.authorLoeffler M
dc.contributor.authorSimon JC
dc.coverage.spatialEngland
dc.date.accessioned2023-11-22T01:36:14Z
dc.date.accessioned2024-07-25T06:48:53Z
dc.date.available2020-01-20
dc.date.available2023-11-22T01:36:14Z
dc.date.available2024-07-25T06:48:53Z
dc.date.issued2020-04
dc.description.abstractBackground Atopic eczema (AE) may be associated with several mental health problems. In Germany, existing data from selected patient cohorts may lead to misestimation of the problem. Objectives We aimed to cross-sectionally determine associations of AE with depression, anxiety, quality of life (QoL) and social interactions in subjects from the population-based LIFE-Adult-Study. Methods Subjects underwent standardized interviews (medical history) and answered standardized questionnaires [Centre of Epidemiologic studies-Depression scale (CES-D), Generalized Anxiety Disorder (GAD-7), Lubben Social Network Scale (LSNS), Short Form Health Survey (SF-8)]. We compared data from subjects with AE with those from subjects with selected other chronic/disabling diseases (cardiovascular, diabetes, cancer) and adjusted for selected sociodemographic parameters. Multivariate binary logistic regression was used for categorical variables, linear regression for continuous variables. Results Out of 9104 adults included (57% female, median age 54 years), 372 (4.1%) had a history of AE. Compared with controls, subjects with AE showed higher scores for depressive symptoms (9.3% vs. 6.3%; P < 0.001) and anxiety (8.4% vs. 5.6%, P < 0.001). Odds ratio (OR) was 1.5 [CI 1.0; 2.3] (P = 0.031) for depression, which was comparable to OR in patients with a history of cancer (OR 1.6 [1–2.3], P = 0.001. OR for anxiety in AE was 1.5 [1.0; 2.2], P < 0.049, which was slightly higher than in diabetes mellitus (OR 1.2) and stroke (OR 1.4). Other than in diabetes and/or stroke, we did not find a significant association between AE and social isolation. QoL scores were lower in AE than in controls (mean 46.9 vs. 48.0, P < 0.001 for physical and 50.6 vs. 52.5, P < 0.001 for mental components). Conclusions Subjects with AE showed higher values for depression and anxiety as well as lower QoL scores compared to controls. With regard to depression, odds in AE and cancer were hardly different. Medical care of AE patients should therefore include mental health evaluation and treatment if indicated.
dc.format.pagination810-816
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/31838777
dc.identifier.citationTreudler R, Zeynalova S, Riedel-Heller SG, Zuelke AE, Roehr S, Hinz A, Glaesmer H, Kage P, Loeffler M, Simon JC. (2020). Depression, anxiety and quality of life in subjects with atopic eczema in a population-based cross-sectional study in Germany.. J Eur Acad Dermatol Venereol. 34. 4. (pp. 810-816).
dc.identifier.doi10.1111/jdv.16148
dc.identifier.eissn1468-3083
dc.identifier.elements-typejournal-article
dc.identifier.issn0926-9959
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70942
dc.languageeng
dc.publisherJohn Wiley & Sons Ltd on behalf of European Academy of Dermatology and Venereology
dc.relation.isPartOfJ Eur Acad Dermatol Venereol
dc.rights(c) 2019 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectAnxiety
dc.subjectCross-Sectional Studies
dc.subjectDepression
dc.subjectEczema
dc.subjectFemale
dc.subjectGermany
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectQuality of Life
dc.subjectSocial Isolation
dc.subjectSurveys and Questionnaires
dc.titleDepression, anxiety and quality of life in subjects with atopic eczema in a population-based cross-sectional study in Germany
dc.typeJournal article
pubs.elements-id455016
pubs.organisational-groupOther
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