Prevention of zoonotic spillover: From relying on response to reducing the risk at source.
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Date
2023-10-05
Open Access Location
Journal Title
Journal ISSN
Volume Title
Publisher
Public Library of Science (PLoS)
Rights
CC0 1.0
Abstract
The devastating impact of Coronavirus Disease 2019 (COVID-19) on human health globally has prompted extensive discussions on how to better prepare for and safeguard against the next pandemic. Zoonotic spillover of pathogens from animals to humans is recognized as the predominant cause of emerging infectious diseases and as the primary cause of recent pandemics [1]. This spillover risk is increased by a range of factors (called drivers) that impact the nature, frequency, and intensity of contact between humans and wild animals. Many of these drivers are related to human impact, for example, deforestation and changes in land use and agricultural practices. While it is clear that the triad of prevention-preparedness-response (P-P-R) is highly relevant, there is much discussion on which of these 3 strategic activities in the field of emerging infectious disease should be prioritized and how to optimally target resources. For this, it is important to understand the scope of the respective activity and the consequences of prioritization.
Description
Keywords
Animals, Humans, Zoonoses, Animals, Wild
Citation
Authored by the members of the One Health High-Level Expert Panel (OHHLEP) , Markotter W, Mettenleiter TC, Adisasmito WB, Almuhairi S, Barton Behravesh C, Bilivogui P, Bukachi SA, Casas N, Cediel Becerra N, Charron DF, Chaudhary A, Ciacci Zanella JR, Cunningham AA, Dar O, Debnath N, Dungu B, Farag E, Gao GF, Hayman DTS, Khaitsa M, Koopmans MPG, Machalaba C, Mackenzie JS, Morand S, Smolenskiy V, Zhou L. (2023). Prevention of zoonotic spillover: From relying on response to reducing the risk at source.. PLoS Pathog. 19. 10. (pp. e1011504-).