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dc.contributor.authorMorgan, W. H.
dc.contributor.authorHazelton, M. L.
dc.contributor.authorBalaratnasingamm, C.
dc.contributor.authorChan, H.
dc.contributor.authorHouse, P. H.
dc.contributor.authorBarry, C. J.
dc.contributor.authorCringle, S. J.
dc.contributor.authorYu, D-Y.
dc.date.accessioned2010-11-25T03:37:25Z
dc.date.accessioned2016-03-06T22:26:15Z
dc.date.accessioned2016-09-07T13:57:52Z
dc.date.availableNO_RESTRICTIONen_US
dc.date.available2010-11-25T03:37:25Z
dc.date.available2016-03-06T22:26:15Z
dc.date.available2016-09-07T13:57:52Z
dc.date.issued2008-12-19
dc.identifier.citationMorgan, W. H., Hazelton, M. L., Balaratnasingamm, C., Chan, H., House, P. H., Barry, C. J., et al. (2009). The association between retinal vein ophthalmodynamometric force change and optic disc excavation. British Journal of Ophthalmology, 93(5), 594-596. doi: 10.1136/bjo.2008.149963en_US
dc.identifier.issn0007-1161
dc.identifier.urihttp://hdl.handle.net/10179/9720
dc.description.abstractAim: Retinal vein ophthalmodynamometric force (ODF) is predictive of future optic disc excavation in glaucoma, but it is not known if variation in ODF affects prognosis. We aimed to assess whether a change in ODF provides additional prognostic information. Methods: 135 eyes of 75 patients with glaucoma or being glaucoma suspects had intraocular pressure (IOP), visual fields, stereo optic disc photography and ODF measured on an initial visit and a subsequent visit at mean 82 (SD 7.3) months later. Corneal thickness and blood pressure were recorded on the latter visit. When venous pulsation was spontaneous, the ODF was recorded as 0 g. Change in ODF was calculated. Flicker stereochronoscopy was used to determine the occurrence of optic disc excavation, which was modelled against the measured variables using multiple mixed effects logistic regression. Results: Change in ODF (p=0.046) was associated with increased excavation. Average IOP (p=0.66) and other variables were not associated. Odds ratio for increased optic disc excavation of 1.045 per gram ODF change (95% CI 1.001 to 1.090) was calculated. Conclusion: Change in retinal vein ODF may provide additional information to assist with glaucoma prognostication and implies a significant relationship between venous change and glaucoma patho-physiology.en_US
dc.language.isoenen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.isformatofhttp://bjo.bmj.com/content/93/5/594en_US
dc.relation.isformatofhttp://dx.doi.org/10.1136/bjo.2008.149963en_US
dc.relation.isbasedonBMJ Publishing Groupen_US
dc.subjectOptic discen_US
dc.subjectRetinal veinen_US
dc.subjectOphthalmodynamometric forceen_US
dc.subjectODFen_US
dc.subjectGlaucomaen_US
dc.subject.otherFields of Research::320000 Medical and Health Sciences::321000 Clinical Sciences::321016 Opthalmology and vision scienceen_US
dc.titleThe association between retinal vein ophthalmodynamometric force change and optic disc excavationen_US
dc.typeJournal Articleen_US
dc.identifier.harvestedMassey_Dark
dc.identifier.harvestedMassey_Dark


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