Transmission dynamics of an antimicrobial resistant Campylobacter jejuni lineage in New Zealand’s commercial poultry network

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dc.citation.volume37
dc.contributor.authorGreening SS
dc.contributor.authorZhang J
dc.contributor.authorMidwinter AC
dc.contributor.authorWilkinson DA
dc.contributor.authorFayaz A
dc.contributor.authorWilliamson DA
dc.contributor.authorAnderson MJ
dc.contributor.authorGates MC
dc.contributor.authorFrench NP
dc.coverage.spatialNetherlands
dc.date.accessioned2023-12-15T01:22:47Z
dc.date.accessioned2024-07-25T06:35:13Z
dc.date.available2021-11-08
dc.date.available2023-12-15T01:22:47Z
dc.date.available2024-07-25T06:35:13Z
dc.date.issued2021-12
dc.description.abstractUnderstanding the relative contribution of different between-farm transmission pathways is essential in guiding recommendations for mitigating disease spread. This study investigated the association between contact pathways linking poultry farms in New Zealand and the genetic relatedness of antimicrobial resistant Campylobacter jejuni Sequence Type 6964 (ST-6964), with the aim of identifying the most likely contact pathways that contributed to its rapid spread across the industry. Whole-genome sequencing was performed on 167C. jejuni ST-6964 isolates sampled from across 30 New Zealand commercial poultry enterprises. The genetic relatedness between isolates was determined using whole genome multilocus sequence typing (wgMLST). Permutational multivariate analysis of variance and distance-based linear models were used to explore the strength of the relationship between pairwise genetic associations among the C. jejuni isolates and each of several pairwise distance matrices, indicating either the geographical distance between farms or the network distance of transportation vehicles. Overall, a significant association was found between the pairwise genetic relatedness of the C. jejuni isolates and the parent company, the road distance and the network distance of transporting feed vehicles. This result suggests that the transportation of feed within the commercial poultry industry as well as other local contacts between flocks, such as the movements of personnel, may have played a significant role in the spread of C. jejuni. However, further information on the historical contact patterns between farms is needed to fully characterise the risk of these pathways and to understand how they could be targeted to reduce the spread of C. jejuni.
dc.format.pagination100521-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/34775297
dc.identifier.citationGreening SS, Zhang J, Midwinter AC, Wilkinson DA, Fayaz A, Williamson DA, Anderson MJ, Gates MC, French NP. (2021). Transmission dynamics of an antimicrobial resistant Campylobacter jejuni lineage in New Zealand's commercial poultry network.. Epidemics. 37. (pp. 100521-).
dc.identifier.doi10.1016/j.epidem.2021.100521
dc.identifier.eissn1878-0067
dc.identifier.elements-typejournal-article
dc.identifier.issn1755-4365
dc.identifier.numberARTN 100521
dc.identifier.piiS1755-4365(21)00067-0
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70485
dc.languageeng
dc.publisherElsevier B.V
dc.relation.isPartOfEpidemics
dc.rights(c) 2021 The Author/s
dc.rightsCC BY-NC-ND 4.0
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCampylobacter jejuni
dc.subjectContact networks
dc.subjectCorrelation matrices
dc.subjectPERMANOVA
dc.subjectPhylodynamics
dc.subjectAnimals
dc.subjectAnti-Infective Agents
dc.subjectCampylobacter Infections
dc.subjectCampylobacter jejuni
dc.subjectChickens
dc.subjectGenotype
dc.subjectNew Zealand
dc.subjectPoultry
dc.titleTransmission dynamics of an antimicrobial resistant Campylobacter jejuni lineage in New Zealand’s commercial poultry network
dc.typeJournal article
pubs.elements-id449610
pubs.organisational-groupOther
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