New Campylobacter Lineages in New Zealand Freshwater: Pathogenesis and Public Health Implications

Simple item page
dc.citation.issue12
dc.citation.volume26
dc.contributor.authorCookson AL
dc.contributor.authorBurgess S
dc.contributor.authorMidwinter AC
dc.contributor.authorMarshall JC
dc.contributor.authorMoinet M
dc.contributor.authorRogers L
dc.contributor.authorFayaz A
dc.contributor.authorBiggs PJ
dc.contributor.authorBrightwell G
dc.coverage.spatialEngland
dc.date.accessioned2025-01-08T19:22:17Z
dc.date.available2025-01-08T19:22:17Z
dc.date.issued2024-12
dc.description.abstractThis study investigated the diversity of thermophilic Campylobacter species isolated from three New Zealand freshwater catchments affected by pastoral and urban activities. Utilising matrix-assisted laser desorption ionisation-time of flight and whole genome sequence analysis, the study identified Campylobacter jejuni (n = 46, 46.0%), C. coli (n = 39, 39%), C. lari (n = 4, 4.0%), and two novel Campylobacter species lineages (n = 11, 11%). Core genome sequence analysis provided evidence of prolonged persistence or continuous faecal shedding of closely related strains. The C. jejuni isolates displayed distinct sequence types (STs) associated with human, ruminant, and environmental sources, whereas the C. coli STs included waterborne ST3302 and ST7774. Recombination events affecting loci implicated in human pathogenesis and environmental persistence were observed, particularly in the cdtABC operon (encoding the cytolethal distending toxin) of non-human C. jejuni STs. A low diversity of antimicrobial resistance genes (aadE-Cc in C. coli), with genotype/phenotype concordance for tetracycline resistance (tetO) in three ST177 isolates, was noted. The data suggest the existence of two types of naturalised waterborne Campylobacter: environmentally persistent strains originating from waterbirds and new environmental species not linked to human campylobacteriosis. Identifying and understanding naturalised Campylobacter species is crucial for accurate waterborne public health risk assessments and the effective allocation of resources for water quality management.
dc.description.confidentialfalse
dc.edition.editionDecember 2024
dc.format.paginatione70016-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/39680962
dc.identifier.citationCookson AL, Burgess S, Midwinter AC, Marshall JC, Moinet M, Rogers L, Fayaz A, Biggs PJ, Brightwell G. (2024). New Campylobacter Lineages in New Zealand Freshwater: Pathogenesis and Public Health Implications.. Environ Microbiol. 26. 12. (pp. e70016-).
dc.identifier.doi10.1111/1462-2920.70016
dc.identifier.eissn1462-2920
dc.identifier.elements-typejournal-article
dc.identifier.issn1462-2912
dc.identifier.numbere70016
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/72336
dc.languageeng
dc.publisherJohn Wiley and Sons
dc.publisher.urihttps://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.70016
dc.relation.isPartOfEnviron Microbiol
dc.rights(c) 2024 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCampylobacter coli
dc.subjectCampylobacter jejuni
dc.subjectland‐use
dc.subjectnaturalised
dc.subjectpathogen
dc.subjectpersistent
dc.subjectwater quality
dc.subjectNew Zealand
dc.subjectFresh Water
dc.subjectHumans
dc.subjectCampylobacter
dc.subjectPhylogeny
dc.subjectPublic Health
dc.subjectCampylobacter Infections
dc.subjectCampylobacter jejuni
dc.subjectAnimals
dc.subjectGenome, Bacterial
dc.subjectCampylobacter coli
dc.subjectDrug Resistance, Bacterial
dc.subjectWhole Genome Sequencing
dc.subjectWater Microbiology
dc.subjectGenotype
dc.titleNew Campylobacter Lineages in New Zealand Freshwater: Pathogenesis and Public Health Implications
dc.typeJournal article
pubs.elements-id492784
pubs.organisational-groupOther
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
Published version.pdf
Size:
3.32 MB
Format:
Adobe Portable Document Format
Description:
492784 PDF.pdf
Download
Thumbnail Image
Name:
Evidence.docx
Size:
87.83 KB
Format:
Microsoft Word XML
Description:
emi70016-sup-0001-supinfo.docx
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
9.22 KB
Format:
Plain Text
Description:
Download
Collections
Journal Articles