B vitamins and homocysteine as determinants of bone health: A literature review of human studies

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dc.citation.issue3
dc.citation.volume36
dc.contributor.authorIlesanmi-Oyelere BL
dc.contributor.authorKruger MC
dc.coverage.spatialEngland
dc.date.accessioned2023-07-12T02:13:31Z
dc.date.accessioned2023-09-04T01:40:41Z
dc.date.available2022-09-18
dc.date.available2023-07-12T02:13:31Z
dc.date.available2023-09-04T01:40:41Z
dc.date.issued2023-06
dc.date.updated2023-07-11T03:52:28Z
dc.description(c) 2022 The Author/s
dc.description.abstractAlthough there are several factors related to bone diseases such as physical activity, gender (oestrogen), race/ethnicity, smoking and alcohol habits, nutrition is a modifiable risk factor that could be employed to prevent or manage the onset of bone health diseases such as osteoporosis in humans. Aside from calcium and vitamin D, B vitamins are a group of water-soluble vitamins that play a vital role in cell metabolism. In this review, current evidence on B vitamins and bone health is assessed. Clinical trials (interventions) indicate that treatment with B vitamins impact the concentrations of total plasma/serum homocysteine concentrations (tHcy); however, most studies have reported the lack of an effect of low homocysteine concentrations on bone turnover markers, bone mineral density or fracture risks. Current studies have been inconsistent in their reports on the role of B vitamins and homocysteine in bone health. More data are therefore required to show the mechanism and effect of tHcy and B vitamins on bone mineral density, bone metabolism and fracture risk.
dc.description.confidentialfalse
dc.edition.editionJune 2023
dc.format.extent1031-1044
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/36056551
dc.identifier.citationIlesanmi-Oyelere BL, Kruger MC. (2023). B vitamins and homocysteine as determinants of bone health: A literature review of human studies.. J Hum Nutr Diet. 36. 3. (pp. 1031-1044).
dc.identifier.doi10.1111/jhn.13080
dc.identifier.eissn1365-277X
dc.identifier.elements-typejournal-article
dc.identifier.harvestedMassey_Dark
dc.identifier.issn0952-3871
dc.identifier.urihttp://hdl.handle.net/10179/19865
dc.languageeng
dc.publisherJohn Wiley and Sons Ltd on behalf of British Dietetic Association
dc.publisher.urihttps://onlinelibrary.wiley.com/doi/10.1111/jhn.13080
dc.relation.isPartOfJ Hum Nutr Diet
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectB vitamins
dc.subjectBMD
dc.subjectbone health
dc.subjectbone metabolism
dc.subjecthomocysteine
dc.subjectosteoporosis
dc.subjectHumans
dc.subjectVitamin B Complex
dc.subjectBone Density
dc.subjectHomocysteine
dc.subjectOsteoporosis
dc.subjectBone and Bones
dc.subjectFractures, Bone
dc.subjectFolic Acid
dc.subjectVitamin B 12
dc.titleB vitamins and homocysteine as determinants of bone health: A literature review of human studies
dc.typeJournal article
pubs.elements-id456802
pubs.organisational-groupOther
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